VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Brinker Capital Investments, LLC's Holding History (CIK: 0001360533)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 12,151 Value ($000) $5,508 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 10,348 Value ($000) $4,052 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 11,341 Value ($000) $5,049 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 9,573 Value ($000) $4,641 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 8,963 Value ($000) $3,609 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 8,809 Value ($000) $4,097 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 9,519 Value ($000) $4,462 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 8,386 Value ($000) $3,505 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 10,009 Value ($000) $4,195 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 10,494 Value ($000) $3,649 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 11,542 Value ($000) $4,062 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 10,880 Value ($000) $3,428 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 7,925 Value ($000) $2,289 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 9,183 Value ($000) $2,659 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 9,663 Value ($000) $2,723 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 13,381 Value ($000) $3,492 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 13,424 Value ($000) $2,948 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 11,123 Value ($000) $2,243 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 11,123 Value ($000) $2,243 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 11,087 Value ($000) $2,383 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 22,683 Value ($000) $5,361 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 9,845 Value ($000) $2,679 Avg Close $275.88 Range $253.97 - $306.08

Q4 2019

Shares 72 Value ($000) $16 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 67 Value ($000) $11 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 503 Value ($000) $92 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 274 Value ($000) $50 Avg Close $184.70 Range $160.95 - $195.81

Q3 2016

Shares 3 Value ($000) $0 Avg Close $94.50 Range $83.50 - $103.73

Q4 2015

Shares 12 Value ($000) $2 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 9 Value ($000) $1 Avg Close $128.47 Range $97.45 - $143.45

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	12,151	$5,508	$431.03	$392.50 - $464.44
Q3 2025	10,348	$4,052	$417.92	$362.50 - $484.56
Q2 2025	11,341	$5,049	$460.83	$416.60 - $510.77
Q1 2025	9,573	$4,641	$466.00	$397.25 - $519.68
Q4 2024	8,963	$3,609	$463.53	$377.85 - $519.88
Q3 2024	8,809	$4,097	$480.37	$456.07 - $510.64
Q2 2024	9,519	$4,462	$434.05	$391.01 - $486.43
Q1 2024	8,386	$3,505	$422.74	$403.43 - $448.40
Q4 2023	10,009	$4,195	$369.42	$341.85 - $413.00
Q3 2023	10,494	$3,649	$349.73	$335.82 - $367.00
Q2 2023	11,542	$4,062	$336.94	$313.47 - $354.94
Q1 2023	10,880	$3,428	$299.93	$282.21 - $325.19
Q4 2022	7,925	$2,289	$304.77	$283.58 - $324.75
Q3 2022	9,183	$2,659	$287.72	$271.61 - $305.95
Q2 2022	9,663	$2,723	$267.66	$233.01 - $293.17
Q1 2022	13,381	$3,492	$237.33	$214.66 - $263.58
Q4 2021	13,424	$2,948	$194.45	$176.36 - $224.49
Q3 2021	11,123	$2,243	$195.24	$180.02 - $204.88
Q2 2021	11,123	$2,243	$209.17	$185.33 - $222.78
Q1 2021	11,087	$2,383	$219.65	$204.62 - $242.99
Q4 2020	22,683	$5,361	$229.44	$202.57 - $280.99
Q3 2020	9,845	$2,679	$275.88	$253.97 - $306.08
Q4 2019	72	$16	$202.38	$165.23 - $225.66
Q3 2019	67	$11	$176.91	$165.27 - $188.44
Q2 2019	503	$92	$174.82	$163.68 - $191.71
Q1 2019	274	$50	$184.70	$160.95 - $195.81
Q3 2016	3	$0	$94.50	$83.50 - $103.73
Q4 2015	12	$2	$120.72	$101.49 - $134.71
Q3 2015	9	$1	$128.47	$97.45 - $143.45