VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Ballentine Partners, LLC's Holding History (CIK: 0001374889)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 5,290 Value ($000) $2,398 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 5,090 Value ($000) $1,993 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 5,428 Value ($000) $2,417 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 5,837 Value ($000) $2,830 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 5,590 Value ($000) $2,251 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 5,471 Value ($000) $2,544 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 5,348 Value ($000) $2,507 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 4,878 Value ($000) $2,039 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 4,569 Value ($000) $1,859 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 4,368 Value ($000) $1,519 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 3,476 Value ($000) $1,223 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 3,345 Value ($000) $1,054 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 2,452 Value ($000) $708 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 2,016 Value ($000) $584 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 1,512 Value ($000) $426 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 1,381 Value ($000) $360 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 1,660 Value ($000) $364 Avg Close $194.45 Range $176.36 - $224.49

Q2 2021

Shares 1,023 Value ($000) $206 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 1,107 Value ($000) $238 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 1,235 Value ($000) $291 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 1,462 Value ($000) $398 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 1,446 Value ($000) $420 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 1,495 Value ($000) $356 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 1,411 Value ($000) $309 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 1,353 Value ($000) $230 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 1,361 Value ($000) $250 Avg Close $174.82 Range $163.68 - $191.71

Q3 2017

Shares 1,825 Value ($000) $277 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 1,828 Value ($000) $295 Avg Close $120.38 Range $107.24 - $137.26

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	5,290	$2,398	$431.03	$392.50 - $464.44
Q3 2025	5,090	$1,993	$417.92	$362.50 - $484.56
Q2 2025	5,428	$2,417	$460.83	$416.60 - $510.77
Q1 2025	5,837	$2,830	$466.00	$397.25 - $519.68
Q4 2024	5,590	$2,251	$463.53	$377.85 - $519.88
Q3 2024	5,471	$2,544	$480.37	$456.07 - $510.64
Q2 2024	5,348	$2,507	$434.05	$391.01 - $486.43
Q1 2024	4,878	$2,039	$422.74	$403.43 - $448.40
Q4 2023	4,569	$1,859	$369.42	$341.85 - $413.00
Q3 2023	4,368	$1,519	$349.73	$335.82 - $367.00
Q2 2023	3,476	$1,223	$336.94	$313.47 - $354.94
Q1 2023	3,345	$1,054	$299.93	$282.21 - $325.19
Q4 2022	2,452	$708	$304.77	$283.58 - $324.75
Q3 2022	2,016	$584	$287.72	$271.61 - $305.95
Q2 2022	1,512	$426	$267.66	$233.01 - $293.17
Q1 2022	1,381	$360	$237.33	$214.66 - $263.58
Q4 2021	1,660	$364	$194.45	$176.36 - $224.49
Q2 2021	1,023	$206	$209.17	$185.33 - $222.78
Q1 2021	1,107	$238	$219.65	$204.62 - $242.99
Q4 2020	1,235	$291	$229.44	$202.57 - $280.99
Q3 2020	1,462	$398	$275.88	$253.97 - $306.08
Q2 2020	1,446	$420	$271.12	$222.39 - $299.21
Q1 2020	1,495	$356	$229.39	$197.47 - $249.85
Q4 2019	1,411	$309	$202.38	$165.23 - $225.66
Q3 2019	1,353	$230	$176.91	$165.27 - $188.44
Q2 2019	1,361	$250	$174.82	$163.68 - $191.71
Q3 2017	1,825	$277	$150.51	$125.50 - $167.86
Q2 2017	1,828	$295	$120.38	$107.24 - $137.26