VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Bedell Frazier Investment Counselling, LLC's Holding History (CIK: 0001388142)

Note: Option positions (PUT/CALL) are excluded.

Q4 2014

Shares 39,770 Value ($000) $4,725 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 68,088 Value ($000) $7,647 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 67,564 Value ($000) $6,397 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 67,114 Value ($000) $4,746 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 67,064 Value ($000) $4,983 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 66,539 Value ($000) $5,045 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 65,884 Value ($000) $5,104 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2014	39,770	$4,725	$112.63	$96.43 - $124.35
Q3 2014	68,088	$7,647	$95.21	$84.41 - $116.88
Q2 2014	67,564	$6,397	$70.12	$59.79 - $98.80
Q1 2014	67,114	$4,746	$79.20	$67.49 - $87.77
Q4 2013	67,064	$4,983	$69.64	$58.06 - $78.38
Q3 2013	66,539	$5,045	$79.58	$73.43 - $89.96
Q2 2013	65,884	$5,104	$73.64	$51.28 - $87.47