VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

LPL Financial LLC's Holding History (CIK: 0001403438)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 276,878 Value ($000) $125,525 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 264,182 Value ($000) $103,464 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 240,616 Value ($000) $107,122 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 216,944 Value ($000) $105,179 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 191,053 Value ($000) $76,937 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 189,713 Value ($000) $88,232 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 209,839 Value ($000) $98,356 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 183,371 Value ($000) $76,651 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 163,636 Value ($000) $66,582 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 173,737 Value ($000) $60,415 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 172,028 Value ($000) $60,538 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 167,500 Value ($000) $52,774 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 165,339 Value ($000) $47,746 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 133,075 Value ($000) $38,530 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 135,816 Value ($000) $38,271 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 136,504 Value ($000) $35,623 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 120,502 Value ($000) $26,462 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 112,583 Value ($000) $20,421 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 73,502 Value ($000) $14,820 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 63,431 Value ($000) $13,631 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 42,696 Value ($000) $10,091 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 44,915 Value ($000) $12,222 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 44,092 Value ($000) $12,800 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 40,228 Value ($000) $9,572 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 37,389 Value ($000) $8,186 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 36,321 Value ($000) $6,154 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 40,274 Value ($000) $7,385 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 43,084 Value ($000) $7,925 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 43,481 Value ($000) $7,205 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 44,246 Value ($000) $8,528 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 41,120 Value ($000) $6,989 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 39,080 Value ($000) $6,369 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 43,026 Value ($000) $6,448 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 37,139 Value ($000) $5,647 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 13,743 Value ($000) $1,771 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 10,102 Value ($000) $1,085 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 13,422 Value ($000) $1,005 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 16,892 Value ($000) $1,460 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 17,604 Value ($000) $1,578 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 8,448 Value ($000) $711 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 7,980 Value ($000) $985 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 13,318 Value ($000) $1,525 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 12,193 Value ($000) $1,571 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 11,459 Value ($000) $1,334 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 7,803 Value ($000) $927 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 6,868 Value ($000) $737 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 3,614 Value ($000) $342 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 3,140 Value ($000) $222 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 2,692 Value ($000) $200 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 13,373 Value ($000) $986 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 23,344 Value ($000) $1,869 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	276,878	$125,525	$431.03	$392.50 - $464.44
Q3 2025	264,182	$103,464	$417.92	$362.50 - $484.56
Q2 2025	240,616	$107,122	$460.83	$416.60 - $510.77
Q1 2025	216,944	$105,179	$466.00	$397.25 - $519.68
Q4 2024	191,053	$76,937	$463.53	$377.85 - $519.88
Q3 2024	189,713	$88,232	$480.37	$456.07 - $510.64
Q2 2024	209,839	$98,356	$434.05	$391.01 - $486.43
Q1 2024	183,371	$76,651	$422.74	$403.43 - $448.40
Q4 2023	163,636	$66,582	$369.42	$341.85 - $413.00
Q3 2023	173,737	$60,415	$349.73	$335.82 - $367.00
Q2 2023	172,028	$60,538	$336.94	$313.47 - $354.94
Q1 2023	167,500	$52,774	$299.93	$282.21 - $325.19
Q4 2022	165,339	$47,746	$304.77	$283.58 - $324.75
Q3 2022	133,075	$38,530	$287.72	$271.61 - $305.95
Q2 2022	135,816	$38,271	$267.66	$233.01 - $293.17
Q1 2022	136,504	$35,623	$237.33	$214.66 - $263.58
Q4 2021	120,502	$26,462	$194.45	$176.36 - $224.49
Q3 2021	112,583	$20,421	$195.24	$180.02 - $204.88
Q2 2021	73,502	$14,820	$209.17	$185.33 - $222.78
Q1 2021	63,431	$13,631	$219.65	$204.62 - $242.99
Q4 2020	42,696	$10,091	$229.44	$202.57 - $280.99
Q3 2020	44,915	$12,222	$275.88	$253.97 - $306.08
Q2 2020	44,092	$12,800	$271.12	$222.39 - $299.21
Q1 2020	40,228	$9,572	$229.39	$197.47 - $249.85
Q4 2019	37,389	$8,186	$202.38	$165.23 - $225.66
Q3 2019	36,321	$6,154	$176.91	$165.27 - $188.44
Q2 2019	40,274	$7,385	$174.82	$163.68 - $191.71
Q1 2019	43,084	$7,925	$184.70	$160.95 - $195.81
Q4 2018	43,481	$7,205	$173.27	$151.80 - $194.92
Q3 2018	44,246	$8,528	$178.07	$164.70 - $193.78
Q2 2018	41,120	$6,989	$155.01	$144.07 - $172.00
Q1 2018	39,080	$6,369	$163.34	$146.21 - $178.15
Q4 2017	43,026	$6,448	$148.07	$136.50 - $158.04
Q3 2017	37,139	$5,647	$150.51	$125.50 - $167.86
Q2 2017	13,743	$1,771	$120.38	$107.24 - $137.26
Q1 2017	10,102	$1,085	$88.04	$73.34 - $111.88
Q4 2016	13,422	$1,005	$81.37	$71.46 - $97.93
Q3 2016	16,892	$1,460	$94.50	$83.50 - $103.73
Q2 2016	17,604	$1,578	$86.41	$75.92 - $96.49
Q1 2016	8,448	$711	$90.45	$75.90 - $124.96
Q4 2015	7,980	$985	$120.72	$101.49 - $134.71
Q3 2015	13,318	$1,525	$128.47	$97.45 - $143.45
Q2 2015	12,193	$1,571	$125.98	$113.68 - $137.50
Q1 2015	11,459	$1,334	$119.81	$103.75 - $136.33
Q4 2014	7,803	$927	$112.63	$96.43 - $124.35
Q3 2014	6,868	$737	$95.21	$84.41 - $116.88
Q2 2014	3,614	$342	$70.12	$59.79 - $98.80
Q1 2014	3,140	$222	$79.20	$67.49 - $87.77
Q4 2013	2,692	$200	$69.64	$58.06 - $78.38
Q3 2013	13,373	$986	$79.58	$73.43 - $89.96
Q2 2013	23,344	$1,869	$73.64	$51.28 - $87.47