VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

ENVESTNET ASSET MANAGEMENT INC's Holding History (CIK: 0001407543)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 471,643 Value ($000) $213,824 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 470,755 Value ($000) $184,366 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 448,988 Value ($000) $199,889 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 470,328 Value ($000) $228,024 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 422,698 Value ($000) $170,220 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 403,068 Value ($000) $187,459 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 415,060 Value ($000) $194,547 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 403,309 Value ($000) $168,587 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 412,629 Value ($000) $167,894 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 411,486 Value ($000) $143,090 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 306,254 Value ($000) $107,774 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 1,451,874 Value ($000) $92,731 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 284,200 Value ($000) $82,071 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 269,432 Value ($000) $78,011 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 255,547 Value ($000) $72,011 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 307,739 Value ($000) $80,311 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 269,240 Value ($000) $59,125 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 248,386 Value ($000) $45,055 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 194,744 Value ($000) $39,266 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 208,677 Value ($000) $44,843 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 188,934 Value ($000) $44,653 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 189,042 Value ($000) $51,442 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 163,441 Value ($000) $47,449 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 114,255 Value ($000) $27,187 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 93,971 Value ($000) $20,575 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 87,350 Value ($000) $14,799 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 83,978 Value ($000) $15,400 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 80,681 Value ($000) $14,841 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 71,535 Value ($000) $11,854 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 12,732 Value ($000) $2,454 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 26,553 Value ($000) $4,514 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 17,666 Value ($000) $2,878 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 33,620 Value ($000) $5,038 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 32,247 Value ($000) $4,901 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 24,159 Value ($000) $3,111 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 18,634 Value ($000) $2,038 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 15,037 Value ($000) $1,109 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 17,705 Value ($000) $1,544 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 26,981 Value ($000) $2,321 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 29,050 Value ($000) $2,309 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 31,047 Value ($000) $3,907 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 34,700 Value ($000) $3,614 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 32,147 Value ($000) $3,970 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 30,252 Value ($000) $3,569 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 190 Value ($000) $23 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 178 Value ($000) $20 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 95 Value ($000) $9 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 156 Value ($000) $11 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 204 Value ($000) $15 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 604 Value ($000) $46 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 594 Value ($000) $48 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	471,643	$213,824	$431.03	$392.50 - $464.44
Q3 2025	470,755	$184,366	$417.92	$362.50 - $484.56
Q2 2025	448,988	$199,889	$460.83	$416.60 - $510.77
Q1 2025	470,328	$228,024	$466.00	$397.25 - $519.68
Q4 2024	422,698	$170,220	$463.53	$377.85 - $519.88
Q3 2024	403,068	$187,459	$480.37	$456.07 - $510.64
Q2 2024	415,060	$194,547	$434.05	$391.01 - $486.43
Q1 2024	403,309	$168,587	$422.74	$403.43 - $448.40
Q4 2023	412,629	$167,894	$369.42	$341.85 - $413.00
Q3 2023	411,486	$143,090	$349.73	$335.82 - $367.00
Q2 2023	306,254	$107,774	$336.94	$313.47 - $354.94
Q1 2023	1,451,874	$92,731	$299.93	$282.21 - $325.19
Q4 2022	284,200	$82,071	$304.77	$283.58 - $324.75
Q3 2022	269,432	$78,011	$287.72	$271.61 - $305.95
Q2 2022	255,547	$72,011	$267.66	$233.01 - $293.17
Q1 2022	307,739	$80,311	$237.33	$214.66 - $263.58
Q4 2021	269,240	$59,125	$194.45	$176.36 - $224.49
Q3 2021	248,386	$45,055	$195.24	$180.02 - $204.88
Q2 2021	194,744	$39,266	$209.17	$185.33 - $222.78
Q1 2021	208,677	$44,843	$219.65	$204.62 - $242.99
Q4 2020	188,934	$44,653	$229.44	$202.57 - $280.99
Q3 2020	189,042	$51,442	$275.88	$253.97 - $306.08
Q2 2020	163,441	$47,449	$271.12	$222.39 - $299.21
Q1 2020	114,255	$27,187	$229.39	$197.47 - $249.85
Q4 2019	93,971	$20,575	$202.38	$165.23 - $225.66
Q3 2019	87,350	$14,799	$176.91	$165.27 - $188.44
Q2 2019	83,978	$15,400	$174.82	$163.68 - $191.71
Q1 2019	80,681	$14,841	$184.70	$160.95 - $195.81
Q4 2018	71,535	$11,854	$173.27	$151.80 - $194.92
Q3 2018	12,732	$2,454	$178.07	$164.70 - $193.78
Q2 2018	26,553	$4,514	$155.01	$144.07 - $172.00
Q1 2018	17,666	$2,878	$163.34	$146.21 - $178.15
Q4 2017	33,620	$5,038	$148.07	$136.50 - $158.04
Q3 2017	32,247	$4,901	$150.51	$125.50 - $167.86
Q2 2017	24,159	$3,111	$120.38	$107.24 - $137.26
Q1 2017	18,634	$2,038	$88.04	$73.34 - $111.88
Q4 2016	15,037	$1,109	$81.37	$71.46 - $97.93
Q3 2016	17,705	$1,544	$94.50	$83.50 - $103.73
Q2 2016	26,981	$2,321	$86.41	$75.92 - $96.49
Q1 2016	29,050	$2,309	$90.45	$75.90 - $124.96
Q4 2015	31,047	$3,907	$120.72	$101.49 - $134.71
Q3 2015	34,700	$3,614	$128.47	$97.45 - $143.45
Q2 2015	32,147	$3,970	$125.98	$113.68 - $137.50
Q1 2015	30,252	$3,569	$119.81	$103.75 - $136.33
Q4 2014	190	$23	$112.63	$96.43 - $124.35
Q3 2014	178	$20	$95.21	$84.41 - $116.88
Q2 2014	95	$9	$70.12	$59.79 - $98.80
Q1 2014	156	$11	$79.20	$67.49 - $87.77
Q4 2013	204	$15	$69.64	$58.06 - $78.38
Q3 2013	604	$46	$79.58	$73.43 - $89.96
Q2 2013	594	$48	$73.64	$51.28 - $87.47