VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

KBC Group NV's Holding History (CIK: 0001411133)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 141,120 Value ($000) $64 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 133,602 Value ($000) $52 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 132,665 Value ($000) $59 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 119,305 Value ($000) $58 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 119,429 Value ($000) $48 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 96,727 Value ($000) $45 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 87,042 Value ($000) $41 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 82,172 Value ($000) $34 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 101,274 Value ($000) $41 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 100,400 Value ($000) $35 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 216,878 Value ($000) $76 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 192,078 Value ($000) $61 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 254,327 Value ($000) $73 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 253,975 Value ($000) $74 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 289,976 Value ($000) $82 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 278,439 Value ($000) $73 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 585,254 Value ($000) $129 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 280,163 Value ($000) $50,819 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 296,146 Value ($000) $59,712 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 253,014 Value ($000) $54,370 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 244,596 Value ($000) $57,808 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 148,218 Value ($000) $40,334 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 122,249 Value ($000) $35,491 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 99,240 Value ($000) $23,614 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 114,769 Value ($000) $25,128 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 115,250 Value ($000) $19,525 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 94,918 Value ($000) $17,406 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 75,898 Value ($000) $13,961 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 62,865 Value ($000) $10,417 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 34,796 Value ($000) $6,707 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 24,377 Value ($000) $4,143 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 19,543 Value ($000) $3,185 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 22,728 Value ($000) $3,406 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 29,157 Value ($000) $4,433 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 26,388 Value ($000) $3,401 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 27,366 Value ($000) $2,992 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 58,439 Value ($000) $4,305 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 75,974 Value ($000) $6,626 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 101,262 Value ($000) $8,711 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 95,207 Value ($000) $7,568 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 42,623 Value ($000) $5,363 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 27,864 Value ($000) $2,902 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 49,622 Value ($000) $6,127 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 59,057 Value ($000) $6,967 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 46,353 Value ($000) $5,507 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 9,182 Value ($000) $1,031 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 19,073 Value ($000) $1,806 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 20,450 Value ($000) $1,446 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 37,496 Value ($000) $2,786 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 20,976 Value ($000) $1,590 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 35,805 Value ($000) $2,867 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	141,120	$64	$431.03	$392.50 - $464.44
Q3 2025	133,602	$52	$417.92	$362.50 - $484.56
Q2 2025	132,665	$59	$460.83	$416.60 - $510.77
Q1 2025	119,305	$58	$466.00	$397.25 - $519.68
Q4 2024	119,429	$48	$463.53	$377.85 - $519.88
Q3 2024	96,727	$45	$480.37	$456.07 - $510.64
Q2 2024	87,042	$41	$434.05	$391.01 - $486.43
Q1 2024	82,172	$34	$422.74	$403.43 - $448.40
Q4 2023	101,274	$41	$369.42	$341.85 - $413.00
Q3 2023	100,400	$35	$349.73	$335.82 - $367.00
Q2 2023	216,878	$76	$336.94	$313.47 - $354.94
Q1 2023	192,078	$61	$299.93	$282.21 - $325.19
Q4 2022	254,327	$73	$304.77	$283.58 - $324.75
Q3 2022	253,975	$74	$287.72	$271.61 - $305.95
Q2 2022	289,976	$82	$267.66	$233.01 - $293.17
Q1 2022	278,439	$73	$237.33	$214.66 - $263.58
Q4 2021	585,254	$129	$194.45	$176.36 - $224.49
Q3 2021	280,163	$50,819	$195.24	$180.02 - $204.88
Q2 2021	296,146	$59,712	$209.17	$185.33 - $222.78
Q1 2021	253,014	$54,370	$219.65	$204.62 - $242.99
Q4 2020	244,596	$57,808	$229.44	$202.57 - $280.99
Q3 2020	148,218	$40,334	$275.88	$253.97 - $306.08
Q2 2020	122,249	$35,491	$271.12	$222.39 - $299.21
Q1 2020	99,240	$23,614	$229.39	$197.47 - $249.85
Q4 2019	114,769	$25,128	$202.38	$165.23 - $225.66
Q3 2019	115,250	$19,525	$176.91	$165.27 - $188.44
Q2 2019	94,918	$17,406	$174.82	$163.68 - $191.71
Q1 2019	75,898	$13,961	$184.70	$160.95 - $195.81
Q4 2018	62,865	$10,417	$173.27	$151.80 - $194.92
Q3 2018	34,796	$6,707	$178.07	$164.70 - $193.78
Q2 2018	24,377	$4,143	$155.01	$144.07 - $172.00
Q1 2018	19,543	$3,185	$163.34	$146.21 - $178.15
Q4 2017	22,728	$3,406	$148.07	$136.50 - $158.04
Q3 2017	29,157	$4,433	$150.51	$125.50 - $167.86
Q2 2017	26,388	$3,401	$120.38	$107.24 - $137.26
Q1 2017	27,366	$2,992	$88.04	$73.34 - $111.88
Q4 2016	58,439	$4,305	$81.37	$71.46 - $97.93
Q3 2016	75,974	$6,626	$94.50	$83.50 - $103.73
Q2 2016	101,262	$8,711	$86.41	$75.92 - $96.49
Q1 2016	95,207	$7,568	$90.45	$75.90 - $124.96
Q4 2015	42,623	$5,363	$120.72	$101.49 - $134.71
Q3 2015	27,864	$2,902	$128.47	$97.45 - $143.45
Q2 2015	49,622	$6,127	$125.98	$113.68 - $137.50
Q1 2015	59,057	$6,967	$119.81	$103.75 - $136.33
Q4 2014	46,353	$5,507	$112.63	$96.43 - $124.35
Q3 2014	9,182	$1,031	$95.21	$84.41 - $116.88
Q2 2014	19,073	$1,806	$70.12	$59.79 - $98.80
Q1 2014	20,450	$1,446	$79.20	$67.49 - $87.77
Q4 2013	37,496	$2,786	$69.64	$58.06 - $78.38
Q3 2013	20,976	$1,590	$79.58	$73.43 - $89.96
Q2 2013	35,805	$2,867	$73.64	$51.28 - $87.47