VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Korea Investment CORP's Holding History (CIK: 0001441689)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 193,435 Value ($000) $87,696 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 205,745 Value ($000) $80,578 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 201,734 Value ($000) $89,812 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 221,180 Value ($000) $107,232 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 207,108 Value ($000) $83,402 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 221,546 Value ($000) $103,037 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 214,800 Value ($000) $100,681 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 238,777 Value ($000) $99,811 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 302,839 Value ($000) $123,222 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 280,341 Value ($000) $97,486 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 354,771 Value ($000) $124,847 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 369,980 Value ($000) $116,570 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 358,271 Value ($000) $103,461 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 356,014 Value ($000) $103,080 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 304,699 Value ($000) $85,861 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 252,209 Value ($000) $65,819 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 223,697 Value ($000) $49,124 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 145,586 Value ($000) $26,408 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 226,201 Value ($000) $45,609 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 221,787 Value ($000) $47,660 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 152,231 Value ($000) $35,978 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 192,800 Value ($000) $52,465 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 187,800 Value ($000) $54,520 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 181,500 Value ($000) $43,188 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 166,800 Value ($000) $36,521 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 178,700 Value ($000) $30,275 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 187,500 Value ($000) $34,384 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 152,600 Value ($000) $28,071 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 147,015 Value ($000) $24,362 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 157,915 Value ($000) $30,437 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 172,302 Value ($000) $29,284 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 124,002 Value ($000) $20,210 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 104,802 Value ($000) $15,706 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 114,002 Value ($000) $17,333 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 113,202 Value ($000) $14,588 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 950 Value ($000) $104 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 292 Value ($000) $22 Avg Close $81.37 Range $71.46 - $97.93

Q1 2016

Shares 127,758 Value ($000) $10,155 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 150,558 Value ($000) $18,944 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 115,958 Value ($000) $12,075 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 106,400 Value ($000) $13,138 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 124,600 Value ($000) $14,699 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 250,700 Value ($000) $29,783 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 210,500 Value ($000) $23,641 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 76,700 Value ($000) $7,262 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 44,600 Value ($000) $3,154 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 153,300 Value ($000) $11,390 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 261,200 Value ($000) $19,804 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 7,000 Value ($000) $559 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	193,435	$87,696	$431.03	$392.50 - $464.44
Q3 2025	205,745	$80,578	$417.92	$362.50 - $484.56
Q2 2025	201,734	$89,812	$460.83	$416.60 - $510.77
Q1 2025	221,180	$107,232	$466.00	$397.25 - $519.68
Q4 2024	207,108	$83,402	$463.53	$377.85 - $519.88
Q3 2024	221,546	$103,037	$480.37	$456.07 - $510.64
Q2 2024	214,800	$100,681	$434.05	$391.01 - $486.43
Q1 2024	238,777	$99,811	$422.74	$403.43 - $448.40
Q4 2023	302,839	$123,222	$369.42	$341.85 - $413.00
Q3 2023	280,341	$97,486	$349.73	$335.82 - $367.00
Q2 2023	354,771	$124,847	$336.94	$313.47 - $354.94
Q1 2023	369,980	$116,570	$299.93	$282.21 - $325.19
Q4 2022	358,271	$103,461	$304.77	$283.58 - $324.75
Q3 2022	356,014	$103,080	$287.72	$271.61 - $305.95
Q2 2022	304,699	$85,861	$267.66	$233.01 - $293.17
Q1 2022	252,209	$65,819	$237.33	$214.66 - $263.58
Q4 2021	223,697	$49,124	$194.45	$176.36 - $224.49
Q3 2021	145,586	$26,408	$195.24	$180.02 - $204.88
Q2 2021	226,201	$45,609	$209.17	$185.33 - $222.78
Q1 2021	221,787	$47,660	$219.65	$204.62 - $242.99
Q4 2020	152,231	$35,978	$229.44	$202.57 - $280.99
Q3 2020	192,800	$52,465	$275.88	$253.97 - $306.08
Q2 2020	187,800	$54,520	$271.12	$222.39 - $299.21
Q1 2020	181,500	$43,188	$229.39	$197.47 - $249.85
Q4 2019	166,800	$36,521	$202.38	$165.23 - $225.66
Q3 2019	178,700	$30,275	$176.91	$165.27 - $188.44
Q2 2019	187,500	$34,384	$174.82	$163.68 - $191.71
Q1 2019	152,600	$28,071	$184.70	$160.95 - $195.81
Q4 2018	147,015	$24,362	$173.27	$151.80 - $194.92
Q3 2018	157,915	$30,437	$178.07	$164.70 - $193.78
Q2 2018	172,302	$29,284	$155.01	$144.07 - $172.00
Q1 2018	124,002	$20,210	$163.34	$146.21 - $178.15
Q4 2017	104,802	$15,706	$148.07	$136.50 - $158.04
Q3 2017	114,002	$17,333	$150.51	$125.50 - $167.86
Q2 2017	113,202	$14,588	$120.38	$107.24 - $137.26
Q1 2017	950	$104	$88.04	$73.34 - $111.88
Q4 2016	292	$22	$81.37	$71.46 - $97.93
Q1 2016	127,758	$10,155	$90.45	$75.90 - $124.96
Q4 2015	150,558	$18,944	$120.72	$101.49 - $134.71
Q3 2015	115,958	$12,075	$128.47	$97.45 - $143.45
Q2 2015	106,400	$13,138	$125.98	$113.68 - $137.50
Q1 2015	124,600	$14,699	$119.81	$103.75 - $136.33
Q4 2014	250,700	$29,783	$112.63	$96.43 - $124.35
Q3 2014	210,500	$23,641	$95.21	$84.41 - $116.88
Q2 2014	76,700	$7,262	$70.12	$59.79 - $98.80
Q1 2014	44,600	$3,154	$79.20	$67.49 - $87.77
Q4 2013	153,300	$11,390	$69.64	$58.06 - $78.38
Q3 2013	261,200	$19,804	$79.58	$73.43 - $89.96
Q2 2013	7,000	$559	$73.64	$51.28 - $87.47