VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Daiwa Securities Group Inc.'s Holding History (CIK: 0001481045)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 70,595 Value ($000) $32 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 67,227 Value ($000) $26 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 75,832 Value ($000) $34 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 71,232 Value ($000) $35 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 65,728 Value ($000) $26 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 57,867 Value ($000) $27 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 43,673 Value ($000) $20 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 43,928 Value ($000) $18 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 36,987 Value ($000) $15 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 36,636 Value ($000) $13 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 31,064 Value ($000) $11 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 30,958 Value ($000) $10 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 29,662 Value ($000) $9 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 29,274 Value ($000) $8,476 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 28,129 Value ($000) $7,926 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 26,547 Value ($000) $6,928 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 23,175 Value ($000) $5,089 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 21,692 Value ($000) $3,935 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 19,793 Value ($000) $3,991 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 18,861 Value ($000) $4,053 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 17,163 Value ($000) $4,056 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 45,453 Value ($000) $12,369 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 31,071 Value ($000) $7,393 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 31,071 Value ($000) $7,393 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 12,432 Value ($000) $2,722 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 12,428 Value ($000) $2,106 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 11,806 Value ($000) $2,165 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 11,745 Value ($000) $2,160 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 10,887 Value ($000) $1,804 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 10,347 Value ($000) $1,994 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 9,814 Value ($000) $1,668 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 10,115 Value ($000) $1,649 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 7,562 Value ($000) $1,133 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 7,561 Value ($000) $1,150 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 7,170 Value ($000) $924 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 6,950 Value ($000) $760 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 6,300 Value ($000) $464 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 6,050 Value ($000) $528 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 5,800 Value ($000) $499 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 5,800 Value ($000) $461 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 38,200 Value ($000) $4,807 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 5,600 Value ($000) $583 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 5,600 Value ($000) $691 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 5,600 Value ($000) $661 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 26,070 Value ($000) $3,097 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 8,640 Value ($000) $970 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 6,500 Value ($000) $615 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 6,500 Value ($000) $460 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 6,500 Value ($000) $483 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 6,500 Value ($000) $493 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 6,500 Value ($000) $520 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	70,595	$32	$431.03	$392.50 - $464.44
Q3 2025	67,227	$26	$417.92	$362.50 - $484.56
Q2 2025	75,832	$34	$460.83	$416.60 - $510.77
Q1 2025	71,232	$35	$466.00	$397.25 - $519.68
Q4 2024	65,728	$26	$463.53	$377.85 - $519.88
Q3 2024	57,867	$27	$480.37	$456.07 - $510.64
Q2 2024	43,673	$20	$434.05	$391.01 - $486.43
Q1 2024	43,928	$18	$422.74	$403.43 - $448.40
Q4 2023	36,987	$15	$369.42	$341.85 - $413.00
Q3 2023	36,636	$13	$349.73	$335.82 - $367.00
Q2 2023	31,064	$11	$336.94	$313.47 - $354.94
Q1 2023	30,958	$10	$299.93	$282.21 - $325.19
Q4 2022	29,662	$9	$304.77	$283.58 - $324.75
Q3 2022	29,274	$8,476	$287.72	$271.61 - $305.95
Q2 2022	28,129	$7,926	$267.66	$233.01 - $293.17
Q1 2022	26,547	$6,928	$237.33	$214.66 - $263.58
Q4 2021	23,175	$5,089	$194.45	$176.36 - $224.49
Q3 2021	21,692	$3,935	$195.24	$180.02 - $204.88
Q2 2021	19,793	$3,991	$209.17	$185.33 - $222.78
Q1 2021	18,861	$4,053	$219.65	$204.62 - $242.99
Q4 2020	17,163	$4,056	$229.44	$202.57 - $280.99
Q3 2020	45,453	$12,369	$275.88	$253.97 - $306.08
Q2 2020	31,071	$7,393	$271.12	$222.39 - $299.21
Q1 2020	31,071	$7,393	$229.39	$197.47 - $249.85
Q4 2019	12,432	$2,722	$202.38	$165.23 - $225.66
Q3 2019	12,428	$2,106	$176.91	$165.27 - $188.44
Q2 2019	11,806	$2,165	$174.82	$163.68 - $191.71
Q1 2019	11,745	$2,160	$184.70	$160.95 - $195.81
Q4 2018	10,887	$1,804	$173.27	$151.80 - $194.92
Q3 2018	10,347	$1,994	$178.07	$164.70 - $193.78
Q2 2018	9,814	$1,668	$155.01	$144.07 - $172.00
Q1 2018	10,115	$1,649	$163.34	$146.21 - $178.15
Q4 2017	7,562	$1,133	$148.07	$136.50 - $158.04
Q3 2017	7,561	$1,150	$150.51	$125.50 - $167.86
Q2 2017	7,170	$924	$120.38	$107.24 - $137.26
Q1 2017	6,950	$760	$88.04	$73.34 - $111.88
Q4 2016	6,300	$464	$81.37	$71.46 - $97.93
Q3 2016	6,050	$528	$94.50	$83.50 - $103.73
Q2 2016	5,800	$499	$86.41	$75.92 - $96.49
Q1 2016	5,800	$461	$90.45	$75.90 - $124.96
Q4 2015	38,200	$4,807	$120.72	$101.49 - $134.71
Q3 2015	5,600	$583	$128.47	$97.45 - $143.45
Q2 2015	5,600	$691	$125.98	$113.68 - $137.50
Q1 2015	5,600	$661	$119.81	$103.75 - $136.33
Q4 2014	26,070	$3,097	$112.63	$96.43 - $124.35
Q3 2014	8,640	$970	$95.21	$84.41 - $116.88
Q2 2014	6,500	$615	$70.12	$59.79 - $98.80
Q1 2014	6,500	$460	$79.20	$67.49 - $87.77
Q4 2013	6,500	$483	$69.64	$58.06 - $78.38
Q3 2013	6,500	$493	$79.58	$73.43 - $89.96
Q2 2013	6,500	$520	$73.64	$51.28 - $87.47