VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Quantbot Technologies LP's Holding History (CIK: 0001512991)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 709 Value ($000) $321 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 3,727 Value ($000) $1,460 Avg Close $417.92 Range $362.50 - $484.56

Q4 2023

Shares 43 Value ($000) $17 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 846 Value ($000) $294 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 573 Value ($000) $202 Avg Close $336.94 Range $313.47 - $354.94

Q4 2022

Shares 7,826 Value ($000) $2,260 Avg Close $304.77 Range $283.58 - $324.75

Q2 2022

Shares 538 Value ($000) $151 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 401 Value ($000) $104 Avg Close $237.33 Range $214.66 - $263.58

Q3 2021

Shares 20,190 Value ($000) $3,662 Avg Close $195.24 Range $180.02 - $204.88

Q1 2021

Shares 5,118 Value ($000) $1,099 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 84 Value ($000) $19 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 5,823 Value ($000) $1,584 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 2,381 Value ($000) $691 Avg Close $271.12 Range $222.39 - $299.21

Q4 2019

Shares 9,743 Value ($000) $2,133 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 6,879 Value ($000) $1,165 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 14,928 Value ($000) $2,737 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 8,701 Value ($000) $1,600 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 10,639 Value ($000) $1,762 Avg Close $173.27 Range $151.80 - $194.92

Q2 2018

Shares 24,762 Value ($000) $4,208 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 22,318 Value ($000) $3,637 Avg Close $163.34 Range $146.21 - $178.15

Q3 2017

Shares 1,506 Value ($000) $228 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 6,841 Value ($000) $881 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 5,895 Value ($000) $644 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 2,202 Value ($000) $162 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 5,821 Value ($000) $507 Avg Close $94.50 Range $83.50 - $103.73

Q1 2016

Shares 4,445 Value ($000) $353 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 4,217 Value ($000) $530 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 8,743 Value ($000) $910 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 8,995 Value ($000) $1,110 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 5,947 Value ($000) $701 Avg Close $119.81 Range $103.75 - $136.33

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	709	$321	$431.03	$392.50 - $464.44
Q3 2025	3,727	$1,460	$417.92	$362.50 - $484.56
Q4 2023	43	$17	$369.42	$341.85 - $413.00
Q3 2023	846	$294	$349.73	$335.82 - $367.00
Q2 2023	573	$202	$336.94	$313.47 - $354.94
Q4 2022	7,826	$2,260	$304.77	$283.58 - $324.75
Q2 2022	538	$151	$267.66	$233.01 - $293.17
Q1 2022	401	$104	$237.33	$214.66 - $263.58
Q3 2021	20,190	$3,662	$195.24	$180.02 - $204.88
Q1 2021	5,118	$1,099	$219.65	$204.62 - $242.99
Q4 2020	84	$19	$229.44	$202.57 - $280.99
Q3 2020	5,823	$1,584	$275.88	$253.97 - $306.08
Q2 2020	2,381	$691	$271.12	$222.39 - $299.21
Q4 2019	9,743	$2,133	$202.38	$165.23 - $225.66
Q3 2019	6,879	$1,165	$176.91	$165.27 - $188.44
Q2 2019	14,928	$2,737	$174.82	$163.68 - $191.71
Q1 2019	8,701	$1,600	$184.70	$160.95 - $195.81
Q4 2018	10,639	$1,762	$173.27	$151.80 - $194.92
Q2 2018	24,762	$4,208	$155.01	$144.07 - $172.00
Q1 2018	22,318	$3,637	$163.34	$146.21 - $178.15
Q3 2017	1,506	$228	$150.51	$125.50 - $167.86
Q2 2017	6,841	$881	$120.38	$107.24 - $137.26
Q1 2017	5,895	$644	$88.04	$73.34 - $111.88
Q4 2016	2,202	$162	$81.37	$71.46 - $97.93
Q3 2016	5,821	$507	$94.50	$83.50 - $103.73
Q1 2016	4,445	$353	$90.45	$75.90 - $124.96
Q4 2015	4,217	$530	$120.72	$101.49 - $134.71
Q3 2015	8,743	$910	$128.47	$97.45 - $143.45
Q2 2015	8,995	$1,110	$125.98	$113.68 - $137.50
Q1 2015	5,947	$701	$119.81	$103.75 - $136.33