VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Twin Tree Management, LP's Holding History (CIK: 0001535588)

Note: Option positions (PUT/CALL) are excluded.

Q1 2025
Shares 8,773 Value ($000) $4,253 Avg Close $466.00 Range $397.25 - $519.68
Q2 2024
Shares 11,661 Value ($000) $5,466 Avg Close $434.05 Range $391.01 - $486.43
Q4 2023
Shares 129,852 Value ($000) $52,835 Avg Close $369.42 Range $341.85 - $413.00
Q3 2023
Shares 80,320 Value ($000) $27,930 Avg Close $349.73 Range $335.82 - $367.00
Q2 2023
Shares 27,457 Value ($000) $9,662 Avg Close $336.94 Range $313.47 - $354.94
Q4 2022
Shares 11,540 Value ($000) $3,333 Avg Close $304.77 Range $283.58 - $324.75
Q3 2022
Shares 29,194 Value ($000) $8,453 Avg Close $287.72 Range $271.61 - $305.95
Q2 2022
Shares 1,828 Value ($000) $515 Avg Close $267.66 Range $233.01 - $293.17
Q1 2022
Shares 136,591 Value ($000) $35,646 Avg Close $237.33 Range $214.66 - $263.58
Q4 2021
Shares 140,819 Value ($000) $30,924 Avg Close $194.45 Range $176.36 - $224.49
Q3 2021
Shares 18,203 Value ($000) $3,302 Avg Close $195.24 Range $180.02 - $204.88
Q2 2021
Shares 10,859 Value ($000) $2,190 Avg Close $209.17 Range $185.33 - $222.78
Q1 2021
Shares 43,267 Value ($000) $9,298 Avg Close $219.65 Range $204.62 - $242.99
Q4 2020
Shares 64 Value ($000) $15 Avg Close $229.44 Range $202.57 - $280.99
Q2 2020
Shares 17,608 Value ($000) $5,112 Avg Close $271.12 Range $222.39 - $299.21
Q1 2020
Shares 11,210 Value ($000) $2,667 Avg Close $229.39 Range $197.47 - $249.85
Q4 2019
Shares 34,620 Value ($000) $7,580 Avg Close $202.38 Range $165.23 - $225.66
Q3 2019
Shares 6,309 Value ($000) $1,069 Avg Close $176.91 Range $165.27 - $188.44
Q2 2019
Shares 8,851 Value ($000) $1,623 Avg Close $174.82 Range $163.68 - $191.71
Q1 2019
Shares 14,804 Value ($000) $2,723 Avg Close $184.70 Range $160.95 - $195.81
Q3 2018
Shares 36,049 Value ($000) $6,948 Avg Close $178.07 Range $164.70 - $193.78
Q2 2018
Shares 17,609 Value ($000) $2,993 Avg Close $155.01 Range $144.07 - $172.00
Q1 2018
Shares 1,104 Value ($000) $180 Avg Close $163.34 Range $146.21 - $178.15
Q4 2017
Shares 50,154 Value ($000) $7,516 Avg Close $148.07 Range $136.50 - $158.04
Q3 2017
Shares 49,832 Value ($000) $7,576 Avg Close $150.51 Range $125.50 - $167.86
Q1 2013
Shares 10,729 Value ($000) $590 Avg Close $48.01 Range $42.72 - $55.93
Q4 2012
Shares 8,851 Value ($000) $371 Avg Close — Range —