VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

LANDSCAPE CAPITAL MANAGEMENT, L.L.C.'s Holding History (CIK: 0001536186)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 18,054 Value ($000) $8,185 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 10,484 Value ($000) $4,106 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 3,079 Value ($000) $1,371 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 3,477 Value ($000) $1,686 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 1,283 Value ($000) $517 Avg Close $463.53 Range $377.85 - $519.88

Q3 2018

Shares 1,122 Value ($000) $216 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 2,371 Value ($000) $403 Avg Close $155.01 Range $144.07 - $172.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	18,054	$8,185	$431.03	$392.50 - $464.44
Q3 2025	10,484	$4,106	$417.92	$362.50 - $484.56
Q2 2025	3,079	$1,371	$460.83	$416.60 - $510.77
Q1 2025	3,477	$1,686	$466.00	$397.25 - $519.68
Q4 2024	1,283	$517	$463.53	$377.85 - $519.88
Q3 2018	1,122	$216	$178.07	$164.70 - $193.78
Q2 2018	2,371	$403	$155.01	$144.07 - $172.00