VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Family Manage LLC's Holding History (CIK: 0001539947)

Note: Option positions (PUT/CALL) are excluded.

Q3 2021

Shares 9,758 Value ($000) $1,770 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 9,781 Value ($000) $1,972 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 10,350 Value ($000) $2,224 Avg Close $219.65 Range $204.62 - $242.99

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2021	9,758	$1,770	$195.24	$180.02 - $204.88
Q2 2021	9,781	$1,972	$209.17	$185.33 - $222.78
Q1 2021	10,350	$2,224	$219.65	$204.62 - $242.99