VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Creative Planning's Holding History (CIK: 0001540235)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 100,513 Value ($000) $45,569 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 94,864 Value ($000) $37,153 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 87,174 Value ($000) $38,810 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 88,840 Value ($000) $43,071 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 79,470 Value ($000) $32,002 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 80,467 Value ($000) $37,424 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 79,117 Value ($000) $37,084 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 75,119 Value ($000) $31,401 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 73,236 Value ($000) $29,799 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 121,528 Value ($000) $42,260 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 69,285 Value ($000) $24,382 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 66,696 Value ($000) $21,014 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 65,460 Value ($000) $18,904 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 8,787 Value ($000) $2,544 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 13,105 Value ($000) $3,693 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 5,825 Value ($000) $1,520 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 6,508 Value ($000) $1,429 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 39,024 Value ($000) $7,079 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 32,110 Value ($000) $6,475 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 6,762 Value ($000) $1,453 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 6,403 Value ($000) $1,513 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 6,432 Value ($000) $1,750 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 3,964 Value ($000) $1,151 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 2,951 Value ($000) $702 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 3,515 Value ($000) $769 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 3,381 Value ($000) $573 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 3,568 Value ($000) $654 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 3,991 Value ($000) $734 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 4,252 Value ($000) $705 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 3,999 Value ($000) $771 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 3,508 Value ($000) $596 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 3,640 Value ($000) $593 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 4,363 Value ($000) $654 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 3,850 Value ($000) $585 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 3,716 Value ($000) $479 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 2,799 Value ($000) $306 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 5,064 Value ($000) $373 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 5,554 Value ($000) $484 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 5,249 Value ($000) $451 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 5,147 Value ($000) $409 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 5,336 Value ($000) $671 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 3,391 Value ($000) $353 Avg Close $128.47 Range $97.45 - $143.45

Q1 2015

Shares 3,045 Value ($000) $359 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 3,082 Value ($000) $366 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 1,263 Value ($000) $142 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 1,909 Value ($000) $181 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 1,362 Value ($000) $96 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 1,252 Value ($000) $93 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 1,244 Value ($000) $94 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 870 Value ($000) $70 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	100,513	$45,569	$431.03	$392.50 - $464.44
Q3 2025	94,864	$37,153	$417.92	$362.50 - $484.56
Q2 2025	87,174	$38,810	$460.83	$416.60 - $510.77
Q1 2025	88,840	$43,071	$466.00	$397.25 - $519.68
Q4 2024	79,470	$32,002	$463.53	$377.85 - $519.88
Q3 2024	80,467	$37,424	$480.37	$456.07 - $510.64
Q2 2024	79,117	$37,084	$434.05	$391.01 - $486.43
Q1 2024	75,119	$31,401	$422.74	$403.43 - $448.40
Q4 2023	73,236	$29,799	$369.42	$341.85 - $413.00
Q3 2023	121,528	$42,260	$349.73	$335.82 - $367.00
Q2 2023	69,285	$24,382	$336.94	$313.47 - $354.94
Q1 2023	66,696	$21,014	$299.93	$282.21 - $325.19
Q4 2022	65,460	$18,904	$304.77	$283.58 - $324.75
Q3 2022	8,787	$2,544	$287.72	$271.61 - $305.95
Q2 2022	13,105	$3,693	$267.66	$233.01 - $293.17
Q1 2022	5,825	$1,520	$237.33	$214.66 - $263.58
Q4 2021	6,508	$1,429	$194.45	$176.36 - $224.49
Q3 2021	39,024	$7,079	$195.24	$180.02 - $204.88
Q2 2021	32,110	$6,475	$209.17	$185.33 - $222.78
Q1 2021	6,762	$1,453	$219.65	$204.62 - $242.99
Q4 2020	6,403	$1,513	$229.44	$202.57 - $280.99
Q3 2020	6,432	$1,750	$275.88	$253.97 - $306.08
Q2 2020	3,964	$1,151	$271.12	$222.39 - $299.21
Q1 2020	2,951	$702	$229.39	$197.47 - $249.85
Q4 2019	3,515	$769	$202.38	$165.23 - $225.66
Q3 2019	3,381	$573	$176.91	$165.27 - $188.44
Q2 2019	3,568	$654	$174.82	$163.68 - $191.71
Q1 2019	3,991	$734	$184.70	$160.95 - $195.81
Q4 2018	4,252	$705	$173.27	$151.80 - $194.92
Q3 2018	3,999	$771	$178.07	$164.70 - $193.78
Q2 2018	3,508	$596	$155.01	$144.07 - $172.00
Q1 2018	3,640	$593	$163.34	$146.21 - $178.15
Q4 2017	4,363	$654	$148.07	$136.50 - $158.04
Q3 2017	3,850	$585	$150.51	$125.50 - $167.86
Q2 2017	3,716	$479	$120.38	$107.24 - $137.26
Q1 2017	2,799	$306	$88.04	$73.34 - $111.88
Q4 2016	5,064	$373	$81.37	$71.46 - $97.93
Q3 2016	5,554	$484	$94.50	$83.50 - $103.73
Q2 2016	5,249	$451	$86.41	$75.92 - $96.49
Q1 2016	5,147	$409	$90.45	$75.90 - $124.96
Q4 2015	5,336	$671	$120.72	$101.49 - $134.71
Q3 2015	3,391	$353	$128.47	$97.45 - $143.45
Q1 2015	3,045	$359	$119.81	$103.75 - $136.33
Q4 2014	3,082	$366	$112.63	$96.43 - $124.35
Q3 2014	1,263	$142	$95.21	$84.41 - $116.88
Q2 2014	1,909	$181	$70.12	$59.79 - $98.80
Q1 2014	1,362	$96	$79.20	$67.49 - $87.77
Q4 2013	1,252	$93	$69.64	$58.06 - $78.38
Q3 2013	1,244	$94	$79.58	$73.43 - $89.96
Q2 2013	870	$70	$73.64	$51.28 - $87.47