VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Mirae Asset Global Investments Co., Ltd.'s Holding History (CIK: 0001569395)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 174,347 Value ($000) $79,042 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 151,056 Value ($000) $59,160 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 144,588 Value ($000) $64,371 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 143,318 Value ($000) $69,547 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 119,549 Value ($000) $48,423 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 102,285 Value ($000) $47,346 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 92,269 Value ($000) $43,598 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 300,856 Value ($000) $104,991 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 296,678 Value ($000) $120,715 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 318,600 Value ($000) $110,790 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 277,568 Value ($000) $97,676 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 284,899 Value ($000) $89,763 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 305,822 Value ($000) $88,316 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 319,967 Value ($000) $92,670 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 335,722 Value ($000) $94,603 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 324,500 Value ($000) $84,685 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 285,187 Value ($000) $62,663 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 247,830 Value ($000) $44,954 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 169,739 Value ($000) $34,224 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 331,087 Value ($000) $71,147 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 510,524 Value ($000) $120,657 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 198,285 Value ($000) $53,540 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 175,183 Value ($000) $50,857 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 264,251 Value ($000) $62,879 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 87,057 Value ($000) $19,060 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 64,829 Value ($000) $10,983 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 57,017 Value ($000) $10,355 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 56,708 Value ($000) $10,401 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 53,903 Value ($000) $8,932 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 47,700 Value ($000) $9,145 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 34,928 Value ($000) $5,614 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 32,250 Value ($000) $5,257 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 29,290 Value ($000) $4,390 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 30,808 Value ($000) $4,661 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 20,737 Value ($000) $2,659 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 18,876 Value ($000) $2,063 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 4,923 Value ($000) $363 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 9,682 Value ($000) $844 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 10,289 Value ($000) $885 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 10,399 Value ($000) $827 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 22,205 Value ($000) $2,795 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 6,441 Value ($000) $670 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 6,791 Value ($000) $838 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 6,571 Value ($000) $775 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 5,384 Value ($000) $639 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 5,372 Value ($000) $604 Avg Close $95.21 Range $84.41 - $116.88

Q2 2013

Shares 6,715 Value ($000) $538 Avg Close $73.64 Range $51.28 - $87.47

Q2 2012

Shares 11,465 Value ($000) $641 Avg Close — Range —

Q1 2012

Shares 12,799 Value ($000) $525 Avg Close — Range —

Q4 2011

Shares 14,021 Value ($000) $466 Avg Close — Range —

Q3 2011

Shares 12,835 Value ($000) $571 Avg Close — Range —

Q2 2011

Shares 13,170 Value ($000) $685 Avg Close — Range —

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	174,347	$79,042	$431.03	$392.50 - $464.44
Q3 2025	151,056	$59,160	$417.92	$362.50 - $484.56
Q2 2025	144,588	$64,371	$460.83	$416.60 - $510.77
Q1 2025	143,318	$69,547	$466.00	$397.25 - $519.68
Q4 2024	119,549	$48,423	$463.53	$377.85 - $519.88
Q3 2024	102,285	$47,346	$480.37	$456.07 - $510.64
Q2 2024	92,269	$43,598	$434.05	$391.01 - $486.43
Q1 2024	300,856	$104,991	$422.74	$403.43 - $448.40
Q4 2023	296,678	$120,715	$369.42	$341.85 - $413.00
Q3 2023	318,600	$110,790	$349.73	$335.82 - $367.00
Q2 2023	277,568	$97,676	$336.94	$313.47 - $354.94
Q1 2023	284,899	$89,763	$299.93	$282.21 - $325.19
Q4 2022	305,822	$88,316	$304.77	$283.58 - $324.75
Q3 2022	319,967	$92,670	$287.72	$271.61 - $305.95
Q2 2022	335,722	$94,603	$267.66	$233.01 - $293.17
Q1 2022	324,500	$84,685	$237.33	$214.66 - $263.58
Q4 2021	285,187	$62,663	$194.45	$176.36 - $224.49
Q3 2021	247,830	$44,954	$195.24	$180.02 - $204.88
Q2 2021	169,739	$34,224	$209.17	$185.33 - $222.78
Q1 2021	331,087	$71,147	$219.65	$204.62 - $242.99
Q4 2020	510,524	$120,657	$229.44	$202.57 - $280.99
Q3 2020	198,285	$53,540	$275.88	$253.97 - $306.08
Q2 2020	175,183	$50,857	$271.12	$222.39 - $299.21
Q1 2020	264,251	$62,879	$229.39	$197.47 - $249.85
Q4 2019	87,057	$19,060	$202.38	$165.23 - $225.66
Q3 2019	64,829	$10,983	$176.91	$165.27 - $188.44
Q2 2019	57,017	$10,355	$174.82	$163.68 - $191.71
Q1 2019	56,708	$10,401	$184.70	$160.95 - $195.81
Q4 2018	53,903	$8,932	$173.27	$151.80 - $194.92
Q3 2018	47,700	$9,145	$178.07	$164.70 - $193.78
Q2 2018	34,928	$5,614	$155.01	$144.07 - $172.00
Q1 2018	32,250	$5,257	$163.34	$146.21 - $178.15
Q4 2017	29,290	$4,390	$148.07	$136.50 - $158.04
Q3 2017	30,808	$4,661	$150.51	$125.50 - $167.86
Q2 2017	20,737	$2,659	$120.38	$107.24 - $137.26
Q1 2017	18,876	$2,063	$88.04	$73.34 - $111.88
Q4 2016	4,923	$363	$81.37	$71.46 - $97.93
Q3 2016	9,682	$844	$94.50	$83.50 - $103.73
Q2 2016	10,289	$885	$86.41	$75.92 - $96.49
Q1 2016	10,399	$827	$90.45	$75.90 - $124.96
Q4 2015	22,205	$2,795	$120.72	$101.49 - $134.71
Q3 2015	6,441	$670	$128.47	$97.45 - $143.45
Q2 2015	6,791	$838	$125.98	$113.68 - $137.50
Q1 2015	6,571	$775	$119.81	$103.75 - $136.33
Q4 2014	5,384	$639	$112.63	$96.43 - $124.35
Q3 2014	5,372	$604	$95.21	$84.41 - $116.88
Q2 2013	6,715	$538	$73.64	$51.28 - $87.47
Q2 2012	11,465	$641	—	—
Q1 2012	12,799	$525	—	—
Q4 2011	14,021	$466	—	—
Q3 2011	12,835	$571	—	—
Q2 2011	13,170	$685	—	—