VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Ohio National Investments, Inc.'s Holding History (CIK: 0001573575)

Note: Option positions (PUT/CALL) are excluded.

Q4 2015

Shares 11,600 Value ($000) $1,460 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 11,425 Value ($000) $1,190 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 11,275 Value ($000) $1,392 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 11,100 Value ($000) $1,309 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 10,775 Value ($000) $1,280 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 10,300 Value ($000) $1,157 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 10,175 Value ($000) $963 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 10,225 Value ($000) $723 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 9,700 Value ($000) $721 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 9,050 Value ($000) $686 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 4,475 Value ($000) $357 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2015	11,600	$1,460	$120.72	$101.49 - $134.71
Q3 2015	11,425	$1,190	$128.47	$97.45 - $143.45
Q2 2015	11,275	$1,392	$125.98	$113.68 - $137.50
Q1 2015	11,100	$1,309	$119.81	$103.75 - $136.33
Q4 2014	10,775	$1,280	$112.63	$96.43 - $124.35
Q3 2014	10,300	$1,157	$95.21	$84.41 - $116.88
Q2 2014	10,175	$963	$70.12	$59.79 - $98.80
Q1 2014	10,225	$723	$79.20	$67.49 - $87.77
Q4 2013	9,700	$721	$69.64	$58.06 - $78.38
Q3 2013	9,050	$686	$79.58	$73.43 - $89.96
Q2 2013	4,475	$357	$73.64	$51.28 - $87.47