VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Advisory Services Network, LLC's Holding History (CIK: 0001573876)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 5,009 Value ($000) $2,271 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 4,847 Value ($000) $1,898 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 6,122 Value ($000) $2,797 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 5,713 Value ($000) $2,770 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 6,796 Value ($000) $2,737 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 7,570 Value ($000) $3,548 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 7,570 Value ($000) $3,548 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 9,751 Value ($000) $4,076 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 7,403 Value ($000) $3,012 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 6,407 Value ($000) $2,228 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 6,955 Value ($000) $2,448 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 7,351 Value ($000) $2,316 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 5,391 Value ($000) $1,557 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 5,583 Value ($000) $1,617 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 4,440 Value ($000) $1,252 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 4,275 Value ($000) $1,117 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 1,909 Value ($000) $419 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 2,702 Value ($000) $490 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 3,670 Value ($000) $740 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 2,934 Value ($000) $632 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 2,082 Value ($000) $492 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 7,242 Value ($000) $1,972 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 10,513 Value ($000) $3,053 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 9,507 Value ($000) $2,262 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 9,378 Value ($000) $2,053 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 4,500 Value ($000) $826 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 4,500 Value ($000) $826 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 6,462 Value ($000) $1,189 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 6,991 Value ($000) $1,158 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 6,087 Value ($000) $1,173 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 6,036 Value ($000) $1,062 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 4,653 Value ($000) $758 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 792 Value ($000) $119 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 181 Value ($000) $28 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 2,709 Value ($000) $349 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 72 Value ($000) $8 Avg Close $88.04 Range $73.34 - $111.88

Q3 2016

Shares 63 Value ($000) $5 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 116 Value ($000) $10 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 63 Value ($000) $5 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 133 Value ($000) $17 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 86 Value ($000) $9 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 192 Value ($000) $24 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 184 Value ($000) $22 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 159 Value ($000) $20 Avg Close $112.63 Range $96.43 - $124.35

Q4 2013

Shares 23 Value ($000) $2 Avg Close $69.64 Range $58.06 - $78.38

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	5,009	$2,271	$431.03	$392.50 - $464.44
Q3 2025	4,847	$1,898	$417.92	$362.50 - $484.56
Q2 2025	6,122	$2,797	$460.83	$416.60 - $510.77
Q1 2025	5,713	$2,770	$466.00	$397.25 - $519.68
Q4 2024	6,796	$2,737	$463.53	$377.85 - $519.88
Q3 2024	7,570	$3,548	$480.37	$456.07 - $510.64
Q2 2024	7,570	$3,548	$434.05	$391.01 - $486.43
Q1 2024	9,751	$4,076	$422.74	$403.43 - $448.40
Q4 2023	7,403	$3,012	$369.42	$341.85 - $413.00
Q3 2023	6,407	$2,228	$349.73	$335.82 - $367.00
Q2 2023	6,955	$2,448	$336.94	$313.47 - $354.94
Q1 2023	7,351	$2,316	$299.93	$282.21 - $325.19
Q4 2022	5,391	$1,557	$304.77	$283.58 - $324.75
Q3 2022	5,583	$1,617	$287.72	$271.61 - $305.95
Q2 2022	4,440	$1,252	$267.66	$233.01 - $293.17
Q1 2022	4,275	$1,117	$237.33	$214.66 - $263.58
Q4 2021	1,909	$419	$194.45	$176.36 - $224.49
Q3 2021	2,702	$490	$195.24	$180.02 - $204.88
Q2 2021	3,670	$740	$209.17	$185.33 - $222.78
Q1 2021	2,934	$632	$219.65	$204.62 - $242.99
Q4 2020	2,082	$492	$229.44	$202.57 - $280.99
Q3 2020	7,242	$1,972	$275.88	$253.97 - $306.08
Q2 2020	10,513	$3,053	$271.12	$222.39 - $299.21
Q1 2020	9,507	$2,262	$229.39	$197.47 - $249.85
Q4 2019	9,378	$2,053	$202.38	$165.23 - $225.66
Q3 2019	4,500	$826	$176.91	$165.27 - $188.44
Q2 2019	4,500	$826	$174.82	$163.68 - $191.71
Q1 2019	6,462	$1,189	$184.70	$160.95 - $195.81
Q4 2018	6,991	$1,158	$173.27	$151.80 - $194.92
Q3 2018	6,087	$1,173	$178.07	$164.70 - $193.78
Q2 2018	6,036	$1,062	$155.01	$144.07 - $172.00
Q1 2018	4,653	$758	$163.34	$146.21 - $178.15
Q4 2017	792	$119	$148.07	$136.50 - $158.04
Q3 2017	181	$28	$150.51	$125.50 - $167.86
Q2 2017	2,709	$349	$120.38	$107.24 - $137.26
Q1 2017	72	$8	$88.04	$73.34 - $111.88
Q3 2016	63	$5	$94.50	$83.50 - $103.73
Q2 2016	116	$10	$86.41	$75.92 - $96.49
Q1 2016	63	$5	$90.45	$75.90 - $124.96
Q4 2015	133	$17	$120.72	$101.49 - $134.71
Q3 2015	86	$9	$128.47	$97.45 - $143.45
Q2 2015	192	$24	$125.98	$113.68 - $137.50
Q1 2015	184	$22	$119.81	$103.75 - $136.33
Q4 2014	159	$20	$112.63	$96.43 - $124.35
Q4 2013	23	$2	$69.64	$58.06 - $78.38