VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Columbia Asset Management's Holding History (CIK: 0001585047)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 2,243 Value ($000) $1,017 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 553 Value ($000) $217 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 498 Value ($000) $222 Avg Close $460.83 Range $416.60 - $510.77

Q4 2024

Shares 802 Value ($000) $323 Avg Close $463.53 Range $377.85 - $519.88

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	2,243	$1,017	$431.03	$392.50 - $464.44
Q3 2025	553	$217	$417.92	$362.50 - $484.56
Q2 2025	498	$222	$460.83	$416.60 - $510.77
Q4 2024	802	$323	$463.53	$377.85 - $519.88