VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

National Pension Service's Holding History (CIK: 0001608046)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 530,841 Value ($000) $240,662 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 512,113 Value ($000) $200,564 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 497,800 Value ($000) $221,621 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 558,929 Value ($000) $270,980 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 527,474 Value ($000) $212,414 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 511,047 Value ($000) $237,678 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 461,645 Value ($000) $216,382 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 454,536 Value ($000) $190,001 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 450,621 Value ($000) $183,353 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 441,493 Value ($000) $155,269 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 432,534 Value ($000) $150,600 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 476,855 Value ($000) $148,855 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 416,092 Value ($000) $120,159 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 405,860 Value ($000) $118,836 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 402,367 Value ($000) $113,383 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 370,884 Value ($000) $96,790 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 379,890 Value ($000) $83,424 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 370,946 Value ($000) $67,286 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 372,046 Value ($000) $75,016 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 367,132 Value ($000) $78,893 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 354,093 Value ($000) $83,686 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 332,176 Value ($000) $88,933 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 332,176 Value ($000) $96,434 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 334,366 Value ($000) $79,562 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 329,905 Value ($000) $72,233 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 295,792 Value ($000) $50,113 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 281,421 Value ($000) $51,607 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 281,289 Value ($000) $51,743 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 271,181 Value ($000) $50,364 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 259,616 Value ($000) $50,038 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 247,055 Value ($000) $36,463 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 227,119 Value ($000) $37,016 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 219,727 Value ($000) $32,928 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 229,046 Value ($000) $34,270 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 220,107 Value ($000) $28,006 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 200,779 Value ($000) $21,542 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 192,970 Value ($000) $14,216 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 179,978 Value ($000) $15,696 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 165,281 Value ($000) $14,217 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 133,139 Value ($000) $10,583 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 127,780 Value ($000) $16,079 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 119,773 Value ($000) $12,473 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 98,455 Value ($000) $12,157 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 88,136 Value ($000) $10,397 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 75,546 Value ($000) $8,975 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 85,707 Value ($000) $9,626 Avg Close $95.21 Range $84.41 - $116.88

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	530,841	$240,662	$431.03	$392.50 - $464.44
Q3 2025	512,113	$200,564	$417.92	$362.50 - $484.56
Q2 2025	497,800	$221,621	$460.83	$416.60 - $510.77
Q1 2025	558,929	$270,980	$466.00	$397.25 - $519.68
Q4 2024	527,474	$212,414	$463.53	$377.85 - $519.88
Q3 2024	511,047	$237,678	$480.37	$456.07 - $510.64
Q2 2024	461,645	$216,382	$434.05	$391.01 - $486.43
Q1 2024	454,536	$190,001	$422.74	$403.43 - $448.40
Q4 2023	450,621	$183,353	$369.42	$341.85 - $413.00
Q3 2023	441,493	$155,269	$349.73	$335.82 - $367.00
Q2 2023	432,534	$150,600	$336.94	$313.47 - $354.94
Q1 2023	476,855	$148,855	$299.93	$282.21 - $325.19
Q4 2022	416,092	$120,159	$304.77	$283.58 - $324.75
Q3 2022	405,860	$118,836	$287.72	$271.61 - $305.95
Q2 2022	402,367	$113,383	$267.66	$233.01 - $293.17
Q1 2022	370,884	$96,790	$237.33	$214.66 - $263.58
Q4 2021	379,890	$83,424	$194.45	$176.36 - $224.49
Q3 2021	370,946	$67,286	$195.24	$180.02 - $204.88
Q2 2021	372,046	$75,016	$209.17	$185.33 - $222.78
Q1 2021	367,132	$78,893	$219.65	$204.62 - $242.99
Q4 2020	354,093	$83,686	$229.44	$202.57 - $280.99
Q3 2020	332,176	$88,933	$275.88	$253.97 - $306.08
Q2 2020	332,176	$96,434	$271.12	$222.39 - $299.21
Q1 2020	334,366	$79,562	$229.39	$197.47 - $249.85
Q4 2019	329,905	$72,233	$202.38	$165.23 - $225.66
Q3 2019	295,792	$50,113	$176.91	$165.27 - $188.44
Q2 2019	281,421	$51,607	$174.82	$163.68 - $191.71
Q1 2019	281,289	$51,743	$184.70	$160.95 - $195.81
Q4 2018	271,181	$50,364	$173.27	$151.80 - $194.92
Q3 2018	259,616	$50,038	$178.07	$164.70 - $193.78
Q2 2018	247,055	$36,463	$155.01	$144.07 - $172.00
Q1 2018	227,119	$37,016	$163.34	$146.21 - $178.15
Q4 2017	219,727	$32,928	$148.07	$136.50 - $158.04
Q3 2017	229,046	$34,270	$150.51	$125.50 - $167.86
Q2 2017	220,107	$28,006	$120.38	$107.24 - $137.26
Q1 2017	200,779	$21,542	$88.04	$73.34 - $111.88
Q4 2016	192,970	$14,216	$81.37	$71.46 - $97.93
Q3 2016	179,978	$15,696	$94.50	$83.50 - $103.73
Q2 2016	165,281	$14,217	$86.41	$75.92 - $96.49
Q1 2016	133,139	$10,583	$90.45	$75.90 - $124.96
Q4 2015	127,780	$16,079	$120.72	$101.49 - $134.71
Q3 2015	119,773	$12,473	$128.47	$97.45 - $143.45
Q2 2015	98,455	$12,157	$125.98	$113.68 - $137.50
Q1 2015	88,136	$10,397	$119.81	$103.75 - $136.33
Q4 2014	75,546	$8,975	$112.63	$96.43 - $124.35
Q3 2014	85,707	$9,626	$95.21	$84.41 - $116.88