VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Trexquant Investment LP's Holding History (CIK: 0001633445)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 46,053 Value ($000) $20,879 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 5,416 Value ($000) $2,121 Avg Close $417.92 Range $362.50 - $484.56

Q1 2024

Shares 5,904 Value ($000) $2,468 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 3,968 Value ($000) $1,615 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 1,519 Value ($000) $528 Avg Close $349.73 Range $335.82 - $367.00

Q1 2023

Shares 4,176 Value ($000) $1,316 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 52,220 Value ($000) $15,080 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 29,180 Value ($000) $8,449 Avg Close $287.72 Range $271.61 - $305.95

Q3 2021

Shares 15,061 Value ($000) $2,732 Avg Close $195.24 Range $180.02 - $204.88

Q3 2020

Shares 18,712 Value ($000) $5,092 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 10,506 Value ($000) $3,050 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 14,357 Value ($000) $3,416 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 27,491 Value ($000) $6,019 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 18,229 Value ($000) $3,088 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 9,202 Value ($000) $1,687 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 23,947 Value ($000) $4,405 Avg Close $184.70 Range $160.95 - $195.81

Q3 2018

Shares 6,646 Value ($000) $1,281 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 29,379 Value ($000) $4,993 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 24,278 Value ($000) $3,957 Avg Close $163.34 Range $146.21 - $178.15

Q3 2017

Shares 5,664 Value ($000) $861 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 2,310 Value ($000) $298 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 16,600 Value ($000) $1,815 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 3,500 Value ($000) $258 Avg Close $81.37 Range $71.46 - $97.93

Q1 2016

Shares 11,500 Value ($000) $914 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 17,800 Value ($000) $2,240 Avg Close $120.72 Range $101.49 - $134.71

Q2 2015

Shares 20,000 Value ($000) $2,469 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 6,000 Value ($000) $707 Avg Close $119.81 Range $103.75 - $136.33

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	46,053	$20,879	$431.03	$392.50 - $464.44
Q3 2025	5,416	$2,121	$417.92	$362.50 - $484.56
Q1 2024	5,904	$2,468	$422.74	$403.43 - $448.40
Q4 2023	3,968	$1,615	$369.42	$341.85 - $413.00
Q3 2023	1,519	$528	$349.73	$335.82 - $367.00
Q1 2023	4,176	$1,316	$299.93	$282.21 - $325.19
Q4 2022	52,220	$15,080	$304.77	$283.58 - $324.75
Q3 2022	29,180	$8,449	$287.72	$271.61 - $305.95
Q3 2021	15,061	$2,732	$195.24	$180.02 - $204.88
Q3 2020	18,712	$5,092	$275.88	$253.97 - $306.08
Q2 2020	10,506	$3,050	$271.12	$222.39 - $299.21
Q1 2020	14,357	$3,416	$229.39	$197.47 - $249.85
Q4 2019	27,491	$6,019	$202.38	$165.23 - $225.66
Q3 2019	18,229	$3,088	$176.91	$165.27 - $188.44
Q2 2019	9,202	$1,687	$174.82	$163.68 - $191.71
Q1 2019	23,947	$4,405	$184.70	$160.95 - $195.81
Q3 2018	6,646	$1,281	$178.07	$164.70 - $193.78
Q2 2018	29,379	$4,993	$155.01	$144.07 - $172.00
Q1 2018	24,278	$3,957	$163.34	$146.21 - $178.15
Q3 2017	5,664	$861	$150.51	$125.50 - $167.86
Q2 2017	2,310	$298	$120.38	$107.24 - $137.26
Q1 2017	16,600	$1,815	$88.04	$73.34 - $111.88
Q4 2016	3,500	$258	$81.37	$71.46 - $97.93
Q1 2016	11,500	$914	$90.45	$75.90 - $124.96
Q4 2015	17,800	$2,240	$120.72	$101.49 - $134.71
Q2 2015	20,000	$2,469	$125.98	$113.68 - $137.50
Q1 2015	6,000	$707	$119.81	$103.75 - $136.33