VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Quadrature Capital Ltd's Holding History (CIK: 0001651424)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,303 Value ($000) $591 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 149,908 Value ($000) $58,695 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 17,913 Value ($000) $7,974 Avg Close $460.83 Range $416.60 - $510.77

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,303	$591	$431.03	$392.50 - $464.44
Q3 2025	149,908	$58,695	$417.92	$362.50 - $484.56
Q2 2025	17,913	$7,974	$460.83	$416.60 - $510.77