VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Intermede Investment Partners Ltd's Holding History (CIK: 0001664713)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 133,378 Value ($000) $60 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 140,023 Value ($000) $55 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 193,915 Value ($000) $86 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 204,045 Value ($000) $99 Avg Close $466.00 Range $397.25 - $519.68

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	133,378	$60	$431.03	$392.50 - $464.44
Q3 2025	140,023	$55	$417.92	$362.50 - $484.56
Q2 2025	193,915	$86	$460.83	$416.60 - $510.77
Q1 2025	204,045	$99	$466.00	$397.25 - $519.68