VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Exane Asset Management's Holding History (CIK: 0001666256)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 100 Value ($000) $46 Avg Close $417.92 Range $362.50 - $484.56

Q2 2021

Shares 206,160 Value ($000) $41,568,041 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 155,252 Value ($000) $33,362,102 Avg Close $219.65 Range $204.62 - $242.99

Q4 2017

Shares 1,300 Value ($000) $194,818 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 903 Value ($000) $137,292 Avg Close $150.51 Range $125.50 - $167.86

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	100	$46	$417.92	$362.50 - $484.56
Q2 2021	206,160	$41,568,041	$209.17	$185.33 - $222.78
Q1 2021	155,252	$33,362,102	$219.65	$204.62 - $242.99
Q4 2017	1,300	$194,818	$148.07	$136.50 - $158.04
Q3 2017	903	$137,292	$150.51	$125.50 - $167.86