VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

AE Wealth Management LLC's Holding History (CIK: 0001697723)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 2,730 Value ($000) $1,238 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 1,772 Value ($000) $694 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 2,468 Value ($000) $1,099 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 1,164 Value ($000) $564 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 1,165 Value ($000) $469 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 1,136 Value ($000) $528 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 1,167 Value ($000) $547 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 1,333 Value ($000) $557 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 22,608 Value ($000) $9,725 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 20,898 Value ($000) $7,267 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 16,547 Value ($000) $5,823 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 1,815 Value ($000) $572 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 4,996 Value ($000) $1,443 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 1,444 Value ($000) $418 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 1,217 Value ($000) $343 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 946 Value ($000) $247 Avg Close $237.33 Range $214.66 - $263.58

Q2 2021

Shares 1,027 Value ($000) $207 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 12,831 Value ($000) $2,757 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 1,049 Value ($000) $248 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 4,404 Value ($000) $1,198 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 2,293 Value ($000) $666 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 4,088 Value ($000) $973 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 1,764 Value ($000) $386 Avg Close $202.38 Range $165.23 - $225.66

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	2,730	$1,238	$431.03	$392.50 - $464.44
Q3 2025	1,772	$694	$417.92	$362.50 - $484.56
Q2 2025	2,468	$1,099	$460.83	$416.60 - $510.77
Q1 2025	1,164	$564	$466.00	$397.25 - $519.68
Q4 2024	1,165	$469	$463.53	$377.85 - $519.88
Q3 2024	1,136	$528	$480.37	$456.07 - $510.64
Q2 2024	1,167	$547	$434.05	$391.01 - $486.43
Q1 2024	1,333	$557	$422.74	$403.43 - $448.40
Q4 2023	22,608	$9,725	$369.42	$341.85 - $413.00
Q3 2023	20,898	$7,267	$349.73	$335.82 - $367.00
Q2 2023	16,547	$5,823	$336.94	$313.47 - $354.94
Q1 2023	1,815	$572	$299.93	$282.21 - $325.19
Q4 2022	4,996	$1,443	$304.77	$283.58 - $324.75
Q3 2022	1,444	$418	$287.72	$271.61 - $305.95
Q2 2022	1,217	$343	$267.66	$233.01 - $293.17
Q1 2022	946	$247	$237.33	$214.66 - $263.58
Q2 2021	1,027	$207	$209.17	$185.33 - $222.78
Q1 2021	12,831	$2,757	$219.65	$204.62 - $242.99
Q4 2020	1,049	$248	$229.44	$202.57 - $280.99
Q3 2020	4,404	$1,198	$275.88	$253.97 - $306.08
Q2 2020	2,293	$666	$271.12	$222.39 - $299.21
Q1 2020	4,088	$973	$229.39	$197.47 - $249.85
Q4 2019	1,764	$386	$202.38	$165.23 - $225.66