VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

ARK Investment Management LLC's Holding History (CIK: 0001697748)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 26,100 Value ($000) $11,833 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 25,665 Value ($000) $10,051 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 24,063 Value ($000) $10,713 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 26,344 Value ($000) $12,772 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 25,350 Value ($000) $10,209 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 51,099 Value ($000) $23,765 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 75,464 Value ($000) $35,371 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 90,104 Value ($000) $37,664 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 124,197 Value ($000) $50,535 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 115,331 Value ($000) $40,105 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 115,671 Value ($000) $40,706 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 120,509 Value ($000) $37,969 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 122,197 Value ($000) $35,288 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 157,445 Value ($000) $45,587 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 365,522 Value ($000) $98,197 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 421,775 Value ($000) $110,071 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 928,791 Value ($000) $203,963 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 1,709,751 Value ($000) $310,132 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 1,774,066 Value ($000) $357,705 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 1,719,046 Value ($000) $369,406 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 816,194 Value ($000) $192,899 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 97,352 Value ($000) $26,491 Avg Close $275.88 Range $253.97 - $306.08

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	26,100	$11,833	$431.03	$392.50 - $464.44
Q3 2025	25,665	$10,051	$417.92	$362.50 - $484.56
Q2 2025	24,063	$10,713	$460.83	$416.60 - $510.77
Q1 2025	26,344	$12,772	$466.00	$397.25 - $519.68
Q4 2024	25,350	$10,209	$463.53	$377.85 - $519.88
Q3 2024	51,099	$23,765	$480.37	$456.07 - $510.64
Q2 2024	75,464	$35,371	$434.05	$391.01 - $486.43
Q1 2024	90,104	$37,664	$422.74	$403.43 - $448.40
Q4 2023	124,197	$50,535	$369.42	$341.85 - $413.00
Q3 2023	115,331	$40,105	$349.73	$335.82 - $367.00
Q2 2023	115,671	$40,706	$336.94	$313.47 - $354.94
Q1 2023	120,509	$37,969	$299.93	$282.21 - $325.19
Q4 2022	122,197	$35,288	$304.77	$283.58 - $324.75
Q3 2022	157,445	$45,587	$287.72	$271.61 - $305.95
Q2 2022	365,522	$98,197	$267.66	$233.01 - $293.17
Q1 2022	421,775	$110,071	$237.33	$214.66 - $263.58
Q4 2021	928,791	$203,963	$194.45	$176.36 - $224.49
Q3 2021	1,709,751	$310,132	$195.24	$180.02 - $204.88
Q2 2021	1,774,066	$357,705	$209.17	$185.33 - $222.78
Q1 2021	1,719,046	$369,406	$219.65	$204.62 - $242.99
Q4 2020	816,194	$192,899	$229.44	$202.57 - $280.99
Q3 2020	97,352	$26,491	$275.88	$253.97 - $306.08