VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Columbus Macro, LLC's Holding History (CIK: 0001727269)

Note: Option positions (PUT/CALL) are excluded.

Q3 2021

Shares 1,617 Value ($000) $293 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 1,618 Value ($000) $326 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 1,568 Value ($000) $337 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 1,677 Value ($000) $396 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 976 Value ($000) $266 Avg Close $275.88 Range $253.97 - $306.08

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2021	1,617	$293	$195.24	$180.02 - $204.88
Q2 2021	1,618	$326	$209.17	$185.33 - $222.78
Q1 2021	1,568	$337	$219.65	$204.62 - $242.99
Q4 2020	1,677	$396	$229.44	$202.57 - $280.99
Q3 2020	976	$266	$275.88	$253.97 - $306.08