VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Integrated Wealth Concepts LLC's Holding History (CIK: 0001737109)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 4,721 Value ($000) $2,140 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 4,574 Value ($000) $1,792 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 4,330 Value ($000) $1,928 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 4,714 Value ($000) $2,285 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 4,902 Value ($000) $1,974 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 5,109 Value ($000) $2,376 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 3,337 Value ($000) $1,564 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 3,178 Value ($000) $1,328 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 2,895 Value ($000) $1,178 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 2,895 Value ($000) $1,007 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 2,910 Value ($000) $1,024 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 1,991 Value ($000) $1 Avg Close $299.93 Range $282.21 - $325.19

Q3 2022

Shares 733 Value ($000) $212 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 784 Value ($000) $221 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 966 Value ($000) $252 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 1,253 Value ($000) $275 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 1,367 Value ($000) $248 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 1,989 Value ($000) $401 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 2,214 Value ($000) $476 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 2,059 Value ($000) $487 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 2,742 Value ($000) $746 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 2,100 Value ($000) $610 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 2,092 Value ($000) $498 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 1,726 Value ($000) $378 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 1,776 Value ($000) $301 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 1,710 Value ($000) $314 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 1,191 Value ($000) $219 Avg Close $184.70 Range $160.95 - $195.81

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	4,721	$2,140	$431.03	$392.50 - $464.44
Q3 2025	4,574	$1,792	$417.92	$362.50 - $484.56
Q2 2025	4,330	$1,928	$460.83	$416.60 - $510.77
Q1 2025	4,714	$2,285	$466.00	$397.25 - $519.68
Q4 2024	4,902	$1,974	$463.53	$377.85 - $519.88
Q3 2024	5,109	$2,376	$480.37	$456.07 - $510.64
Q2 2024	3,337	$1,564	$434.05	$391.01 - $486.43
Q1 2024	3,178	$1,328	$422.74	$403.43 - $448.40
Q4 2023	2,895	$1,178	$369.42	$341.85 - $413.00
Q3 2023	2,895	$1,007	$349.73	$335.82 - $367.00
Q2 2023	2,910	$1,024	$336.94	$313.47 - $354.94
Q1 2023	1,991	$1	$299.93	$282.21 - $325.19
Q3 2022	733	$212	$287.72	$271.61 - $305.95
Q2 2022	784	$221	$267.66	$233.01 - $293.17
Q1 2022	966	$252	$237.33	$214.66 - $263.58
Q4 2021	1,253	$275	$194.45	$176.36 - $224.49
Q3 2021	1,367	$248	$195.24	$180.02 - $204.88
Q2 2021	1,989	$401	$209.17	$185.33 - $222.78
Q1 2021	2,214	$476	$219.65	$204.62 - $242.99
Q4 2020	2,059	$487	$229.44	$202.57 - $280.99
Q3 2020	2,742	$746	$275.88	$253.97 - $306.08
Q2 2020	2,100	$610	$271.12	$222.39 - $299.21
Q1 2020	2,092	$498	$229.39	$197.47 - $249.85
Q4 2019	1,726	$378	$202.38	$165.23 - $225.66
Q3 2019	1,776	$301	$176.91	$165.27 - $188.44
Q2 2019	1,710	$314	$174.82	$163.68 - $191.71
Q1 2019	1,191	$219	$184.70	$160.95 - $195.81