VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Aigen Investment Management, LP's Holding History (CIK: 0001741224)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 894 Value ($000) $405 Avg Close $431.03 Range $392.50 - $464.44

Q2 2024

Shares 1,274 Value ($000) $597 Avg Close $434.05 Range $391.01 - $486.43

Q2 2023

Shares 4,358 Value ($000) $1,534 Avg Close $336.94 Range $313.47 - $354.94

Q3 2022

Shares 6,692 Value ($000) $1,938 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 1,256 Value ($000) $354 Avg Close $267.66 Range $233.01 - $293.17

Q4 2021

Shares 4,059 Value ($000) $867 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 9,524 Value ($000) $1,728 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 30,131 Value ($000) $6,075 Avg Close $209.17 Range $185.33 - $222.78

Q3 2020

Shares 20,899 Value ($000) $5,687 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 28,703 Value ($000) $8,333 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 27,214 Value ($000) $6,476 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 19,177 Value ($000) $4,199 Avg Close $202.38 Range $165.23 - $225.66

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	894	$405	$431.03	$392.50 - $464.44
Q2 2024	1,274	$597	$434.05	$391.01 - $486.43
Q2 2023	4,358	$1,534	$336.94	$313.47 - $354.94
Q3 2022	6,692	$1,938	$287.72	$271.61 - $305.95
Q2 2022	1,256	$354	$267.66	$233.01 - $293.17
Q4 2021	4,059	$867	$194.45	$176.36 - $224.49
Q3 2021	9,524	$1,728	$195.24	$180.02 - $204.88
Q2 2021	30,131	$6,075	$209.17	$185.33 - $222.78
Q3 2020	20,899	$5,687	$275.88	$253.97 - $306.08
Q2 2020	28,703	$8,333	$271.12	$222.39 - $299.21
Q1 2020	27,214	$6,476	$229.39	$197.47 - $249.85
Q4 2019	19,177	$4,199	$202.38	$165.23 - $225.66