VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Beacon Pointe Advisors, LLC's Holding History (CIK: 0001744317)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 13,502 Value ($000) $6,121 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 13,284 Value ($000) $5,203 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 16,029 Value ($000) $7,136 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 16,225 Value ($000) $7,866 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 16,203 Value ($000) $6,525 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 16,996 Value ($000) $7,905 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 19,181 Value ($000) $8,991 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 19,189 Value ($000) $8,021 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 19,264 Value ($000) $7,838 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 20,077 Value ($000) $6,982 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 19,353 Value ($000) $6,811 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 21,106 Value ($000) $6,650 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 26,336 Value ($000) $7,605 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 26,882 Value ($000) $7,793 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 27,179 Value ($000) $7,664 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 27,932 Value ($000) $7,289 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 22,518 Value ($000) $4,945 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 28,832 Value ($000) $5,230 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 10,987 Value ($000) $2,215 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 1,451 Value ($000) $313 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 1,381 Value ($000) $327 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 1,564 Value ($000) $426 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 1,402 Value ($000) $408 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 1,389 Value ($000) $329 Avg Close $229.39 Range $197.47 - $249.85

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	13,502	$6,121	$431.03	$392.50 - $464.44
Q3 2025	13,284	$5,203	$417.92	$362.50 - $484.56
Q2 2025	16,029	$7,136	$460.83	$416.60 - $510.77
Q1 2025	16,225	$7,866	$466.00	$397.25 - $519.68
Q4 2024	16,203	$6,525	$463.53	$377.85 - $519.88
Q3 2024	16,996	$7,905	$480.37	$456.07 - $510.64
Q2 2024	19,181	$8,991	$434.05	$391.01 - $486.43
Q1 2024	19,189	$8,021	$422.74	$403.43 - $448.40
Q4 2023	19,264	$7,838	$369.42	$341.85 - $413.00
Q3 2023	20,077	$6,982	$349.73	$335.82 - $367.00
Q2 2023	19,353	$6,811	$336.94	$313.47 - $354.94
Q1 2023	21,106	$6,650	$299.93	$282.21 - $325.19
Q4 2022	26,336	$7,605	$304.77	$283.58 - $324.75
Q3 2022	26,882	$7,793	$287.72	$271.61 - $305.95
Q2 2022	27,179	$7,664	$267.66	$233.01 - $293.17
Q1 2022	27,932	$7,289	$237.33	$214.66 - $263.58
Q4 2021	22,518	$4,945	$194.45	$176.36 - $224.49
Q3 2021	28,832	$5,230	$195.24	$180.02 - $204.88
Q2 2021	10,987	$2,215	$209.17	$185.33 - $222.78
Q1 2021	1,451	$313	$219.65	$204.62 - $242.99
Q4 2020	1,381	$327	$229.44	$202.57 - $280.99
Q3 2020	1,564	$426	$275.88	$253.97 - $306.08
Q2 2020	1,402	$408	$271.12	$222.39 - $299.21
Q1 2020	1,389	$329	$229.39	$197.47 - $249.85