VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Old North State Trust, LLC's Holding History (CIK: 0001760444)

Note: Option positions (PUT/CALL) are excluded.

Q1 2023

Shares 100 Value ($000) $0 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 100 Value ($000) $0 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 100 Value ($000) $29 Avg Close $287.72 Range $271.61 - $305.95

Q4 2021

Shares 100 Value ($000) $22 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 100 Value ($000) $18 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 100 Value ($000) $20 Avg Close $209.17 Range $185.33 - $222.78

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2023	100	$0	$299.93	$282.21 - $325.19
Q4 2022	100	$0	$304.77	$283.58 - $324.75
Q3 2022	100	$29	$287.72	$271.61 - $305.95
Q4 2021	100	$22	$194.45	$176.36 - $224.49
Q3 2021	100	$18	$195.24	$180.02 - $204.88
Q2 2021	100	$20	$209.17	$185.33 - $222.78