VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Advisor OS, LLC's Holding History (CIK: 0001767580)

Note: Option positions (PUT/CALL) are excluded.

Q1 2025

Shares 543 Value ($000) $263 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 520 Value ($000) $209 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 538 Value ($000) $250 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 545 Value ($000) $255 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 494 Value ($000) $206 Avg Close $422.74 Range $403.43 - $448.40

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2025	543	$263	$466.00	$397.25 - $519.68
Q4 2024	520	$209	$463.53	$377.85 - $519.88
Q3 2024	538	$250	$480.37	$456.07 - $510.64
Q2 2024	545	$255	$434.05	$391.01 - $486.43
Q1 2024	494	$206	$422.74	$403.43 - $448.40