VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Y-Intercept (Hong Kong) Ltd's Holding History (CIK: 0001772875)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 27,770 Value ($000) $10,876 Avg Close $417.92 Range $362.50 - $484.56

Q4 2024

Shares 5,385 Value ($000) $2,169 Avg Close $463.53 Range $377.85 - $519.88

Q2 2024

Shares 4,683 Value ($000) $2,195 Avg Close $434.05 Range $391.01 - $486.43

Q4 2022

Shares 9,719 Value ($000) $2,807 Avg Close $304.77 Range $283.58 - $324.75

Q4 2021

Shares 7,996 Value ($000) $1,756 Avg Close $194.45 Range $176.36 - $224.49

Q1 2021

Shares 2,579 Value ($000) $549 Avg Close $219.65 Range $204.62 - $242.99

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	27,770	$10,876	$417.92	$362.50 - $484.56
Q4 2024	5,385	$2,169	$463.53	$377.85 - $519.88
Q2 2024	4,683	$2,195	$434.05	$391.01 - $486.43
Q4 2022	9,719	$2,807	$304.77	$283.58 - $324.75
Q4 2021	7,996	$1,756	$194.45	$176.36 - $224.49
Q1 2021	2,579	$549	$219.65	$204.62 - $242.99