VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

IEQ CAPITAL, LLC's Holding History (CIK: 0001779789)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 22,524 Value ($000) $10,212 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 6,451 Value ($000) $2,527 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 16,219 Value ($000) $7,220 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 22,005 Value ($000) $10,668 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 18,223 Value ($000) $7,338 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 22,581 Value ($000) $10,502 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 21,093 Value ($000) $9,887 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 19,216 Value ($000) $8,032 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 17,983 Value ($000) $7,317 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 17,483 Value ($000) $6,080 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 16,484 Value ($000) $5,801 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 14,846 Value ($000) $4,677 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 14,359 Value ($000) $4,146 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 13,519 Value ($000) $3,914 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 8,644 Value ($000) $2,436 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 7,043 Value ($000) $1,838 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 5,844 Value ($000) $1,283 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 3,635 Value ($000) $659 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 2,407 Value ($000) $485 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 2,509 Value ($000) $539 Avg Close $219.65 Range $204.62 - $242.99

Q3 2020

Shares 2,078 Value ($000) $565 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 2,191 Value ($000) $636 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 2,204 Value ($000) $524 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 1,516 Value ($000) $332 Avg Close $202.38 Range $165.23 - $225.66

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	22,524	$10,212	$431.03	$392.50 - $464.44
Q3 2025	6,451	$2,527	$417.92	$362.50 - $484.56
Q2 2025	16,219	$7,220	$460.83	$416.60 - $510.77
Q1 2025	22,005	$10,668	$466.00	$397.25 - $519.68
Q4 2024	18,223	$7,338	$463.53	$377.85 - $519.88
Q3 2024	22,581	$10,502	$480.37	$456.07 - $510.64
Q2 2024	21,093	$9,887	$434.05	$391.01 - $486.43
Q1 2024	19,216	$8,032	$422.74	$403.43 - $448.40
Q4 2023	17,983	$7,317	$369.42	$341.85 - $413.00
Q3 2023	17,483	$6,080	$349.73	$335.82 - $367.00
Q2 2023	16,484	$5,801	$336.94	$313.47 - $354.94
Q1 2023	14,846	$4,677	$299.93	$282.21 - $325.19
Q4 2022	14,359	$4,146	$304.77	$283.58 - $324.75
Q3 2022	13,519	$3,914	$287.72	$271.61 - $305.95
Q2 2022	8,644	$2,436	$267.66	$233.01 - $293.17
Q1 2022	7,043	$1,838	$237.33	$214.66 - $263.58
Q4 2021	5,844	$1,283	$194.45	$176.36 - $224.49
Q3 2021	3,635	$659	$195.24	$180.02 - $204.88
Q2 2021	2,407	$485	$209.17	$185.33 - $222.78
Q1 2021	2,509	$539	$219.65	$204.62 - $242.99
Q3 2020	2,078	$565	$275.88	$253.97 - $306.08
Q2 2020	2,191	$636	$271.12	$222.39 - $299.21
Q1 2020	2,204	$524	$229.39	$197.47 - $249.85
Q4 2019	1,516	$332	$202.38	$165.23 - $225.66