VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Ethic Inc.'s Holding History (CIK: 0001780570)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 15,983 Value ($000) $7,246 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 13,971 Value ($000) $5,472 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 11,495 Value ($000) $5,073 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 11,437 Value ($000) $5,544 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 22,990 Value ($000) $9,258 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 19,793 Value ($000) $8,274 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 21,162 Value ($000) $9,919 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 19,793 Value ($000) $8,274 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 17,636 Value ($000) $7,176 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 16,505 Value ($000) $5,739 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 14,736 Value ($000) $5,186 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 13,314 Value ($000) $4,195 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 8,703 Value ($000) $2,513 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 7,331 Value ($000) $2,123 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 6,005 Value ($000) $1,692 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 2,349 Value ($000) $613 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 2,192 Value ($000) $481 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 4,086 Value ($000) $741 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 4,210 Value ($000) $849 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 3,461 Value ($000) $744 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 2,495 Value ($000) $590 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 2,599 Value ($000) $707 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 2,368 Value ($000) $687 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 948 Value ($000) $226 Avg Close $229.39 Range $197.47 - $249.85

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	15,983	$7,246	$431.03	$392.50 - $464.44
Q3 2025	13,971	$5,472	$417.92	$362.50 - $484.56
Q2 2025	11,495	$5,073	$460.83	$416.60 - $510.77
Q1 2025	11,437	$5,544	$466.00	$397.25 - $519.68
Q4 2024	22,990	$9,258	$463.53	$377.85 - $519.88
Q3 2024	19,793	$8,274	$480.37	$456.07 - $510.64
Q2 2024	21,162	$9,919	$434.05	$391.01 - $486.43
Q1 2024	19,793	$8,274	$422.74	$403.43 - $448.40
Q4 2023	17,636	$7,176	$369.42	$341.85 - $413.00
Q3 2023	16,505	$5,739	$349.73	$335.82 - $367.00
Q2 2023	14,736	$5,186	$336.94	$313.47 - $354.94
Q1 2023	13,314	$4,195	$299.93	$282.21 - $325.19
Q4 2022	8,703	$2,513	$304.77	$283.58 - $324.75
Q3 2022	7,331	$2,123	$287.72	$271.61 - $305.95
Q2 2022	6,005	$1,692	$267.66	$233.01 - $293.17
Q1 2022	2,349	$613	$237.33	$214.66 - $263.58
Q4 2021	2,192	$481	$194.45	$176.36 - $224.49
Q3 2021	4,086	$741	$195.24	$180.02 - $204.88
Q2 2021	4,210	$849	$209.17	$185.33 - $222.78
Q1 2021	3,461	$744	$219.65	$204.62 - $242.99
Q4 2020	2,495	$590	$229.44	$202.57 - $280.99
Q3 2020	2,599	$707	$275.88	$253.97 - $306.08
Q2 2020	2,368	$687	$271.12	$222.39 - $299.21
Q1 2020	948	$226	$229.39	$197.47 - $249.85