VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Capital Group Private Client Services, Inc.'s Holding History (CIK: 0001857666)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 23,852 Value ($000) $10,814 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 24,874 Value ($000) $9,742 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 104,537 Value ($000) $46,540 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 25,632 Value ($000) $12,427 Avg Close $466.00 Range $397.25 - $519.68

Q1 2022

Shares 57,226 Value ($000) $14,934 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 57,166 Value ($000) $12,554 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 62,137 Value ($000) $11,271 Avg Close $195.24 Range $180.02 - $204.88

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	23,852	$10,814	$431.03	$392.50 - $464.44
Q3 2025	24,874	$9,742	$417.92	$362.50 - $484.56
Q2 2025	104,537	$46,540	$460.83	$416.60 - $510.77
Q1 2025	25,632	$12,427	$466.00	$397.25 - $519.68
Q1 2022	57,226	$14,934	$237.33	$214.66 - $263.58
Q4 2021	57,166	$12,554	$194.45	$176.36 - $224.49
Q3 2021	62,137	$11,271	$195.24	$180.02 - $204.88