VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Graphene Investments SAS's Holding History (CIK: 0001965776)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 7,500 Value ($000) $3,400 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 8,300 Value ($000) $3,251 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 6,800 Value ($000) $3,027 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 5,500 Value ($000) $2,667 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 6,500 Value ($000) $2,618 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 7,100 Value ($000) $3,302 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 7,100 Value ($000) $3,328 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 8,200 Value ($000) $3,428 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 8,200 Value ($000) $3,336 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 9,000 Value ($000) $3,130 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 9,000 Value ($000) $3,167 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 10,200 Value ($000) $3,214 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 9,600 Value ($000) $2,772 Avg Close $304.77 Range $283.58 - $324.75

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	7,500	$3,400	$431.03	$392.50 - $464.44
Q3 2025	8,300	$3,251	$417.92	$362.50 - $484.56
Q2 2025	6,800	$3,027	$460.83	$416.60 - $510.77
Q1 2025	5,500	$2,667	$466.00	$397.25 - $519.68
Q4 2024	6,500	$2,618	$463.53	$377.85 - $519.88
Q3 2024	7,100	$3,302	$480.37	$456.07 - $510.64
Q2 2024	7,100	$3,328	$434.05	$391.01 - $486.43
Q1 2024	8,200	$3,428	$422.74	$403.43 - $448.40
Q4 2023	8,200	$3,336	$369.42	$341.85 - $413.00
Q3 2023	9,000	$3,130	$349.73	$335.82 - $367.00
Q2 2023	9,000	$3,167	$336.94	$313.47 - $354.94
Q1 2023	10,200	$3,214	$299.93	$282.21 - $325.19
Q4 2022	9,600	$2,772	$304.77	$283.58 - $324.75