VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Sienna Gestion's Holding History (CIK: 0002021242)

Note: Option positions (PUT/CALL) are excluded.

Q4 2024

Shares 514 Value ($000) $207 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 21,243 Value ($000) $9,856 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 18,019 Value ($000) $8,442 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 18,019 Value ($000) $7,532 Avg Close $422.74 Range $403.43 - $448.40

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2024	514	$207	$463.53	$377.85 - $519.88
Q3 2024	21,243	$9,856	$480.37	$456.07 - $510.64
Q2 2024	18,019	$8,442	$434.05	$391.01 - $486.43
Q1 2024	18,019	$7,532	$422.74	$403.43 - $448.40