VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

KEYNOTE FINANCIAL SERVICES LLC's Holding History (CIK: 0002026127)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,166 Value ($000) $529 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 1,154 Value ($000) $452 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 1,145 Value ($000) $510 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 1,105 Value ($000) $536 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 1,085 Value ($000) $437 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 1,070 Value ($000) $498 Avg Close $480.37 Range $456.07 - $510.64

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,166	$529	$431.03	$392.50 - $464.44
Q3 2025	1,154	$452	$417.92	$362.50 - $484.56
Q2 2025	1,145	$510	$460.83	$416.60 - $510.77
Q1 2025	1,105	$536	$466.00	$397.25 - $519.68
Q4 2024	1,085	$437	$463.53	$377.85 - $519.88
Q3 2024	1,070	$498	$480.37	$456.07 - $510.64