VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Aviso Financial Inc.'s Holding History (CIK: 0002033534)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 3,052 Value ($000) $1,384 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 3,165 Value ($000) $1,240 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 1,844 Value ($000) $821 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 1,850 Value ($000) $897 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 1,203 Value ($000) $484 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 1,187 Value ($000) $552 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 965 Value ($000) $452 Avg Close $434.05 Range $391.01 - $486.43

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	3,052	$1,384	$431.03	$392.50 - $464.44
Q3 2025	3,165	$1,240	$417.92	$362.50 - $484.56
Q2 2025	1,844	$821	$460.83	$416.60 - $510.77
Q1 2025	1,850	$897	$466.00	$397.25 - $519.68
Q4 2024	1,203	$484	$463.53	$377.85 - $519.88
Q3 2024	1,187	$552	$480.37	$456.07 - $510.64
Q2 2024	965	$452	$434.05	$391.01 - $486.43