VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Generali Asset Management SPA SGR's Holding History (CIK: 0002046751)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 18,538 Value ($000) $8,404 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 23,569 Value ($000) $9,231 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 16,627 Value ($000) $7,402 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 18,332 Value ($000) $8,888 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 22,861 Value ($000) $9,206 Avg Close $463.53 Range $377.85 - $519.88

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	18,538	$8,404	$431.03	$392.50 - $464.44
Q3 2025	23,569	$9,231	$417.92	$362.50 - $484.56
Q2 2025	16,627	$7,402	$460.83	$416.60 - $510.77
Q1 2025	18,332	$8,888	$466.00	$397.25 - $519.68
Q4 2024	22,861	$9,206	$463.53	$377.85 - $519.88