VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Banque Transatlantique SA's Holding History (CIK: 0002056095)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 539 Value ($000) $244 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 614 Value ($000) $240 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 776 Value ($000) $346 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 824 Value ($000) $399 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 612 Value ($000) $248 Avg Close $463.53 Range $377.85 - $519.88

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	539	$244	$431.03	$392.50 - $464.44
Q3 2025	614	$240	$417.92	$362.50 - $484.56
Q2 2025	776	$346	$460.83	$416.60 - $510.77
Q1 2025	824	$399	$466.00	$397.25 - $519.68
Q4 2024	612	$248	$463.53	$377.85 - $519.88