VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

TFR Capital, LLC.'s Holding History (CIK: 0002059325)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 5,026 Value ($000) $2,279 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 4,935 Value ($000) $1,933 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 4,950 Value ($000) $2,204 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 4,756 Value ($000) $2,306 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 4,561 Value ($000) $1,837 Avg Close $463.53 Range $377.85 - $519.88

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	5,026	$2,279	$431.03	$392.50 - $464.44
Q3 2025	4,935	$1,933	$417.92	$362.50 - $484.56
Q2 2025	4,950	$2,204	$460.83	$416.60 - $510.77
Q1 2025	4,756	$2,306	$466.00	$397.25 - $519.68
Q4 2024	4,561	$1,837	$463.53	$377.85 - $519.88