XENON PHARMACEUTICALS INC

Ticker: XENE CUSIP: 98420N105 Class: Common Stock

STATE STREET CORP's Holding History (CIK: 0000093751)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,492,550 Value ($000) $66,896 Avg Close $42.00 Range $37.23 - $46.60

Q3 2025

Shares 1,466,467 Value ($000) $58,879 Avg Close $35.22 Range $30.00 - $40.35

Q2 2025

Shares 1,380,460 Value ($000) $43,208 Avg Close $32.62 Range $26.74 - $39.01

Q1 2025

Shares 305,620 Value ($000) $10,254 Avg Close $37.97 Range $32.70 - $42.23

Q4 2024

Shares 288,722 Value ($000) $11,318 Avg Close $41.35 Range $37.34 - $46.00

Q3 2024

Shares 279,513 Value ($000) $11,004 Avg Close $40.32 Range $35.73 - $44.74

Q2 2024

Shares 246,812 Value ($000) $9,623 Avg Close $39.97 Range $35.53 - $44.37

Q1 2024

Shares 242,640 Value ($000) $10,446 Avg Close $46.00 Range $42.08 - $50.99

Q4 2023

Shares 227,040 Value ($000) $10,457 Avg Close $35.33 Range $27.98 - $47.00

Q3 2023

Shares 212,370 Value ($000) $7,255 Avg Close $37.40 Range $33.93 - $40.13

Q2 2023

Shares 212,550 Value ($000) $8,183 Avg Close $39.75 Range $33.60 - $43.75

Q1 2023

Shares 207,456 Value ($000) $7,425 Avg Close $36.94 Range $32.64 - $41.25

Q4 2022

Shares 197,436 Value ($000) $7,785 Avg Close $36.42 Range $31.79 - $40.06

Q3 2022

Shares 170,371 Value ($000) $6,150 Avg Close $35.95 Range $28.98 - $41.39

Q2 2022

Shares 197,221 Value ($000) $5,999 Avg Close $30.24 Range $24.94 - $35.69

Q1 2022

Shares 171,987 Value ($000) $5,258 Avg Close $29.94 Range $24.60 - $33.45

Q4 2021

Shares 161,249 Value ($000) $5,037 Avg Close $29.88 Range $15.29 - $36.42

Q3 2021

Shares 147,447 Value ($000) $2,253 Avg Close $17.38 Range $14.65 - $19.64

Q2 2021

Shares 130,595 Value ($000) $2,432 Avg Close $18.43 Range $16.30 - $21.52

Q1 2021

Shares 98,088 Value ($000) $1,756 Avg Close $16.95 Range $13.23 - $21.94

Q4 2020

Shares 93,386 Value ($000) $1,436 Avg Close $11.70 Range $9.32 - $16.41

Q3 2020

Shares 89,547 Value ($000) $991 Avg Close $11.77 Range $10.11 - $14.10

Q2 2020

Shares 86,664 Value ($000) $1,087 Avg Close $12.73 Range $9.96 - $17.00

Q1 2020

Shares 18,978 Value ($000) $215 Avg Close $14.24 Range $7.00 - $18.45

Q4 2019

Shares 20,360 Value ($000) $267 Avg Close $10.52 Range $7.88 - $14.95

Q3 2019

Shares 20,664 Value ($000) $186 Avg Close $9.46 Range $8.54 - $10.90

Q2 2019

Shares 20,664 Value ($000) $204 Avg Close $9.57 Range $8.22 - $11.34

Q1 2019

Shares 20,664 Value ($000) $210 Avg Close $8.48 Range $6.17 - $10.74

Q4 2018

Shares 21,288 Value ($000) $134 Avg Close $8.89 Range $5.41 - $13.49

Q3 2018

Shares 19,500 Value ($000) $257 Avg Close $11.59 Range $8.85 - $15.92

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,492,550	$66,896	$42.00	$37.23 - $46.60
Q3 2025	1,466,467	$58,879	$35.22	$30.00 - $40.35
Q2 2025	1,380,460	$43,208	$32.62	$26.74 - $39.01
Q1 2025	305,620	$10,254	$37.97	$32.70 - $42.23
Q4 2024	288,722	$11,318	$41.35	$37.34 - $46.00
Q3 2024	279,513	$11,004	$40.32	$35.73 - $44.74
Q2 2024	246,812	$9,623	$39.97	$35.53 - $44.37
Q1 2024	242,640	$10,446	$46.00	$42.08 - $50.99
Q4 2023	227,040	$10,457	$35.33	$27.98 - $47.00
Q3 2023	212,370	$7,255	$37.40	$33.93 - $40.13
Q2 2023	212,550	$8,183	$39.75	$33.60 - $43.75
Q1 2023	207,456	$7,425	$36.94	$32.64 - $41.25
Q4 2022	197,436	$7,785	$36.42	$31.79 - $40.06
Q3 2022	170,371	$6,150	$35.95	$28.98 - $41.39
Q2 2022	197,221	$5,999	$30.24	$24.94 - $35.69
Q1 2022	171,987	$5,258	$29.94	$24.60 - $33.45
Q4 2021	161,249	$5,037	$29.88	$15.29 - $36.42
Q3 2021	147,447	$2,253	$17.38	$14.65 - $19.64
Q2 2021	130,595	$2,432	$18.43	$16.30 - $21.52
Q1 2021	98,088	$1,756	$16.95	$13.23 - $21.94
Q4 2020	93,386	$1,436	$11.70	$9.32 - $16.41
Q3 2020	89,547	$991	$11.77	$10.11 - $14.10
Q2 2020	86,664	$1,087	$12.73	$9.96 - $17.00
Q1 2020	18,978	$215	$14.24	$7.00 - $18.45
Q4 2019	20,360	$267	$10.52	$7.88 - $14.95
Q3 2019	20,664	$186	$9.46	$8.54 - $10.90
Q2 2019	20,664	$204	$9.57	$8.22 - $11.34
Q1 2019	20,664	$210	$8.48	$6.17 - $10.74
Q4 2018	21,288	$134	$8.89	$5.41 - $13.49
Q3 2018	19,500	$257	$11.59	$8.85 - $15.92