XENON PHARMACEUTICALS INC

Ticker: XENE CUSIP: 98420N105 Class: Common Stock

Granahan Investment Management, LLC's Holding History (CIK: 0001026710)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 92,778 Value ($000) $4,158 Avg Close $42.00 Range $37.23 - $46.60

Q3 2025

Shares 87,470 Value ($000) $3,512 Avg Close $35.22 Range $30.00 - $40.35

Q2 2025

Shares 240,038 Value ($000) $7,513 Avg Close $32.62 Range $26.74 - $39.01

Q1 2025

Shares 183,808 Value ($000) $6,167 Avg Close $37.97 Range $32.70 - $42.23

Q4 2024

Shares 182,333 Value ($000) $7,147 Avg Close $41.35 Range $37.34 - $46.00

Q3 2024

Shares 200,877 Value ($000) $7,909 Avg Close $40.32 Range $35.73 - $44.74

Q2 2024

Shares 226,166 Value ($000) $8,818 Avg Close $39.97 Range $35.53 - $44.37

Q1 2024

Shares 244,080 Value ($000) $10,508 Avg Close $46.00 Range $42.08 - $50.99

Q4 2023

Shares 302,581 Value ($000) $13,937 Avg Close $35.33 Range $27.98 - $47.00

Q3 2023

Shares 236,290 Value ($000) $8,072 Avg Close $37.40 Range $33.93 - $40.13

Q2 2023

Shares 236,753 Value ($000) $9,115 Avg Close $39.75 Range $33.60 - $43.75

Q1 2023

Shares 276,012 Value ($000) $9,878 Avg Close $36.94 Range $32.64 - $41.25

Q4 2022

Shares 324,250 Value ($000) $12,785 Avg Close $36.42 Range $31.79 - $40.06

Q3 2022

Shares 299,855 Value ($000) $10,825 Avg Close $35.95 Range $28.98 - $41.39

Q2 2022

Shares 284,772 Value ($000) $8,663 Avg Close $30.24 Range $24.94 - $35.69

Q1 2022

Shares 262,705 Value ($000) $8,031 Avg Close $29.94 Range $24.60 - $33.45

Q4 2021

Shares 217,301 Value ($000) $6,788 Avg Close $29.88 Range $15.29 - $36.42

Q3 2021

Shares 83,854 Value ($000) $1,281 Avg Close $17.38 Range $14.65 - $19.64

Q2 2021

Shares 83,249 Value ($000) $1,550 Avg Close $18.43 Range $16.30 - $21.52

Q1 2021

Shares 83,088 Value ($000) $1,487 Avg Close $16.95 Range $13.23 - $21.94

Q4 2020

Shares 153,321 Value ($000) $2,358 Avg Close $11.70 Range $9.32 - $16.41

Q3 2020

Shares 158,704 Value ($000) $1,757 Avg Close $11.77 Range $10.11 - $14.10

Q2 2020

Shares 110,999 Value ($000) $1,392 Avg Close $12.73 Range $9.96 - $17.00

Q1 2020

Shares 110,999 Value ($000) $1,259 Avg Close $14.24 Range $7.00 - $18.45

Q4 2019

Shares 106,839 Value ($000) $1,401 Avg Close $10.52 Range $7.88 - $14.95

Q3 2019

Shares 106,459 Value ($000) $959 Avg Close $9.46 Range $8.54 - $10.90

Q2 2019

Shares 98,259 Value ($000) $969 Avg Close $9.57 Range $8.22 - $11.34

Q1 2019

Shares 108,679 Value ($000) $1,104 Avg Close $8.48 Range $6.17 - $10.74

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	92,778	$4,158	$42.00	$37.23 - $46.60
Q3 2025	87,470	$3,512	$35.22	$30.00 - $40.35
Q2 2025	240,038	$7,513	$32.62	$26.74 - $39.01
Q1 2025	183,808	$6,167	$37.97	$32.70 - $42.23
Q4 2024	182,333	$7,147	$41.35	$37.34 - $46.00
Q3 2024	200,877	$7,909	$40.32	$35.73 - $44.74
Q2 2024	226,166	$8,818	$39.97	$35.53 - $44.37
Q1 2024	244,080	$10,508	$46.00	$42.08 - $50.99
Q4 2023	302,581	$13,937	$35.33	$27.98 - $47.00
Q3 2023	236,290	$8,072	$37.40	$33.93 - $40.13
Q2 2023	236,753	$9,115	$39.75	$33.60 - $43.75
Q1 2023	276,012	$9,878	$36.94	$32.64 - $41.25
Q4 2022	324,250	$12,785	$36.42	$31.79 - $40.06
Q3 2022	299,855	$10,825	$35.95	$28.98 - $41.39
Q2 2022	284,772	$8,663	$30.24	$24.94 - $35.69
Q1 2022	262,705	$8,031	$29.94	$24.60 - $33.45
Q4 2021	217,301	$6,788	$29.88	$15.29 - $36.42
Q3 2021	83,854	$1,281	$17.38	$14.65 - $19.64
Q2 2021	83,249	$1,550	$18.43	$16.30 - $21.52
Q1 2021	83,088	$1,487	$16.95	$13.23 - $21.94
Q4 2020	153,321	$2,358	$11.70	$9.32 - $16.41
Q3 2020	158,704	$1,757	$11.77	$10.11 - $14.10
Q2 2020	110,999	$1,392	$12.73	$9.96 - $17.00
Q1 2020	110,999	$1,259	$14.24	$7.00 - $18.45
Q4 2019	106,839	$1,401	$10.52	$7.88 - $14.95
Q3 2019	106,459	$959	$9.46	$8.54 - $10.90
Q2 2019	98,259	$969	$9.57	$8.22 - $11.34
Q1 2019	108,679	$1,104	$8.48	$6.17 - $10.74