XENON PHARMACEUTICALS INC

Ticker: XENE CUSIP: 98420N105 Class: Common Stock

MILLENNIUM MANAGEMENT LLC's Holding History (CIK: 0001273087)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 635,056 Value ($000) $28,463 Avg Close $42.00 Range $37.23 - $46.60

Q3 2025

Shares 1,384,007 Value ($000) $55,568 Avg Close $35.22 Range $30.00 - $40.35

Q2 2025

Shares 882,835 Value ($000) $27,633 Avg Close $32.62 Range $26.74 - $39.01

Q1 2025

Shares 234,056 Value ($000) $7,853 Avg Close $37.97 Range $32.70 - $42.23

Q4 2024

Shares 346,040 Value ($000) $13,565 Avg Close $41.35 Range $37.34 - $46.00

Q3 2024

Shares 209,026 Value ($000) $8,229 Avg Close $40.32 Range $35.73 - $44.74

Q2 2024

Shares 175,584 Value ($000) $6,846 Avg Close $39.97 Range $35.53 - $44.37

Q1 2024

Shares 83,661 Value ($000) $3,602 Avg Close $46.00 Range $42.08 - $50.99

Q4 2023

Shares 76,965 Value ($000) $3,545 Avg Close $35.33 Range $27.98 - $47.00

Q3 2023

Shares 95,493 Value ($000) $3,262 Avg Close $37.40 Range $33.93 - $40.13

Q2 2023

Shares 213,338 Value ($000) $8,214 Avg Close $39.75 Range $33.60 - $43.75

Q1 2023

Shares 221,470 Value ($000) $8 Avg Close $36.94 Range $32.64 - $41.25

Q4 2022

Shares 594,541 Value ($000) $23 Avg Close $36.42 Range $31.79 - $40.06

Q3 2022

Shares 560,349 Value ($000) $20,229 Avg Close $35.95 Range $28.98 - $41.39

Q2 2022

Shares 492,691 Value ($000) $14,988 Avg Close $30.24 Range $24.94 - $35.69

Q1 2022

Shares 136,326 Value ($000) $4,167 Avg Close $29.94 Range $24.60 - $33.45

Q4 2021

Shares 90,621 Value ($000) $2,831 Avg Close $29.88 Range $15.29 - $36.42

Q3 2021

Shares 236,219 Value ($000) $3,609 Avg Close $17.38 Range $14.65 - $19.64

Q2 2021

Shares 301,748 Value ($000) $5,619 Avg Close $18.43 Range $16.30 - $21.52

Q1 2021

Shares 342,899 Value ($000) $6,138 Avg Close $16.95 Range $13.23 - $21.94

Q4 2020

Shares 416,475 Value ($000) $6,405 Avg Close $11.70 Range $9.32 - $16.41

Q3 2020

Shares 118,845 Value ($000) $1,316 Avg Close $11.77 Range $10.11 - $14.10

Q2 2020

Shares 167,996 Value ($000) $2,107 Avg Close $12.73 Range $9.96 - $17.00

Q1 2020

Shares 193,569 Value ($000) $2,195 Avg Close $14.24 Range $7.00 - $18.45

Q4 2019

Shares 47,714 Value ($000) $626 Avg Close $10.52 Range $7.88 - $14.95

Q1 2019

Shares 48,286 Value ($000) $491 Avg Close $8.48 Range $6.17 - $10.74

Q4 2018

Shares 145,382 Value ($000) $917 Avg Close $8.89 Range $5.41 - $13.49

Q3 2018

Shares 82,873 Value ($000) $1,094 Avg Close $11.59 Range $8.85 - $15.92

Q4 2016

Shares 193,674 Value ($000) $1,491 Avg Close $8.03 Range $7.35 - $8.75

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	635,056	$28,463	$42.00	$37.23 - $46.60
Q3 2025	1,384,007	$55,568	$35.22	$30.00 - $40.35
Q2 2025	882,835	$27,633	$32.62	$26.74 - $39.01
Q1 2025	234,056	$7,853	$37.97	$32.70 - $42.23
Q4 2024	346,040	$13,565	$41.35	$37.34 - $46.00
Q3 2024	209,026	$8,229	$40.32	$35.73 - $44.74
Q2 2024	175,584	$6,846	$39.97	$35.53 - $44.37
Q1 2024	83,661	$3,602	$46.00	$42.08 - $50.99
Q4 2023	76,965	$3,545	$35.33	$27.98 - $47.00
Q3 2023	95,493	$3,262	$37.40	$33.93 - $40.13
Q2 2023	213,338	$8,214	$39.75	$33.60 - $43.75
Q1 2023	221,470	$8	$36.94	$32.64 - $41.25
Q4 2022	594,541	$23	$36.42	$31.79 - $40.06
Q3 2022	560,349	$20,229	$35.95	$28.98 - $41.39
Q2 2022	492,691	$14,988	$30.24	$24.94 - $35.69
Q1 2022	136,326	$4,167	$29.94	$24.60 - $33.45
Q4 2021	90,621	$2,831	$29.88	$15.29 - $36.42
Q3 2021	236,219	$3,609	$17.38	$14.65 - $19.64
Q2 2021	301,748	$5,619	$18.43	$16.30 - $21.52
Q1 2021	342,899	$6,138	$16.95	$13.23 - $21.94
Q4 2020	416,475	$6,405	$11.70	$9.32 - $16.41
Q3 2020	118,845	$1,316	$11.77	$10.11 - $14.10
Q2 2020	167,996	$2,107	$12.73	$9.96 - $17.00
Q1 2020	193,569	$2,195	$14.24	$7.00 - $18.45
Q4 2019	47,714	$626	$10.52	$7.88 - $14.95
Q1 2019	48,286	$491	$8.48	$6.17 - $10.74
Q4 2018	145,382	$917	$8.89	$5.41 - $13.49
Q3 2018	82,873	$1,094	$11.59	$8.85 - $15.92
Q4 2016	193,674	$1,491	$8.03	$7.35 - $8.75