XENON PHARMACEUTICALS INC

Ticker: XENE CUSIP: 98420N105 Class: Common Stock

Swiss National Bank's Holding History (CIK: 0001582202)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 114,000 Value ($000) $5,109 Avg Close $42.00 Range $37.23 - $46.60

Q3 2025

Shares 126,400 Value ($000) $5,075 Avg Close $35.22 Range $30.00 - $40.35

Q2 2025

Shares 124,300 Value ($000) $3,891 Avg Close $32.62 Range $26.74 - $39.01

Q1 2025

Shares 125,600 Value ($000) $4,214 Avg Close $37.97 Range $32.70 - $42.23

Q4 2024

Shares 126,600 Value ($000) $4,963 Avg Close $41.35 Range $37.34 - $46.00

Q3 2024

Shares 125,300 Value ($000) $4,933 Avg Close $40.32 Range $35.73 - $44.74

Q2 2024

Shares 126,100 Value ($000) $4,917 Avg Close $39.97 Range $35.53 - $44.37

Q1 2024

Shares 123,800 Value ($000) $5,330 Avg Close $46.00 Range $42.08 - $50.99

Q4 2023

Shares 123,800 Value ($000) $5,702 Avg Close $35.33 Range $27.98 - $47.00

Q3 2023

Shares 111,700 Value ($000) $3,816 Avg Close $37.40 Range $33.93 - $40.13

Q2 2023

Shares 109,800 Value ($000) $4,227 Avg Close $39.75 Range $33.60 - $43.75

Q1 2023

Shares 101,300 Value ($000) $3,626 Avg Close $36.94 Range $32.64 - $41.25

Q4 2022

Shares 112,700 Value ($000) $4,444 Avg Close $36.42 Range $31.79 - $40.06

Q3 2022

Shares 108,400 Value ($000) $3,913 Avg Close $35.95 Range $28.98 - $41.39

Q2 2022

Shares 107,800 Value ($000) $3,279 Avg Close $30.24 Range $24.94 - $35.69

Q1 2022

Shares 97,500 Value ($000) $2,981 Avg Close $29.94 Range $24.60 - $33.45

Q4 2021

Shares 87,400 Value ($000) $2,730 Avg Close $29.88 Range $15.29 - $36.42

Q3 2021

Shares 63,400 Value ($000) $969 Avg Close $17.38 Range $14.65 - $19.64

Q2 2021

Shares 61,900 Value ($000) $1,153 Avg Close $18.43 Range $16.30 - $21.52

Q1 2021

Shares 64,000 Value ($000) $1,146 Avg Close $16.95 Range $13.23 - $21.94

Q4 2020

Shares 62,500 Value ($000) $961 Avg Close $11.70 Range $9.32 - $16.41

Q3 2020

Shares 62,500 Value ($000) $692 Avg Close $11.77 Range $10.11 - $14.10

Q2 2020

Shares 62,500 Value ($000) $784 Avg Close $12.73 Range $9.96 - $17.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	114,000	$5,109	$42.00	$37.23 - $46.60
Q3 2025	126,400	$5,075	$35.22	$30.00 - $40.35
Q2 2025	124,300	$3,891	$32.62	$26.74 - $39.01
Q1 2025	125,600	$4,214	$37.97	$32.70 - $42.23
Q4 2024	126,600	$4,963	$41.35	$37.34 - $46.00
Q3 2024	125,300	$4,933	$40.32	$35.73 - $44.74
Q2 2024	126,100	$4,917	$39.97	$35.53 - $44.37
Q1 2024	123,800	$5,330	$46.00	$42.08 - $50.99
Q4 2023	123,800	$5,702	$35.33	$27.98 - $47.00
Q3 2023	111,700	$3,816	$37.40	$33.93 - $40.13
Q2 2023	109,800	$4,227	$39.75	$33.60 - $43.75
Q1 2023	101,300	$3,626	$36.94	$32.64 - $41.25
Q4 2022	112,700	$4,444	$36.42	$31.79 - $40.06
Q3 2022	108,400	$3,913	$35.95	$28.98 - $41.39
Q2 2022	107,800	$3,279	$30.24	$24.94 - $35.69
Q1 2022	97,500	$2,981	$29.94	$24.60 - $33.45
Q4 2021	87,400	$2,730	$29.88	$15.29 - $36.42
Q3 2021	63,400	$969	$17.38	$14.65 - $19.64
Q2 2021	61,900	$1,153	$18.43	$16.30 - $21.52
Q1 2021	64,000	$1,146	$16.95	$13.23 - $21.94
Q4 2020	62,500	$961	$11.70	$9.32 - $16.41
Q3 2020	62,500	$692	$11.77	$10.11 - $14.10
Q2 2020	62,500	$784	$12.73	$9.96 - $17.00