ZENAS BIOPHARMA INC

Ticker: ZBIO CUSIP: 98937L105 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 15,100 Value ($000) $548 Avg Close $32.89 Range $18.33 - $44.60

Q3 2025

Shares 20,382 Value ($000) $452 Avg Close $16.28 Range $8.91 - $22.45

Q2 2025

Shares 19,617 Value ($000) $190 Avg Close $9.74 Range $6.11 - $12.56

Q4 2024

Shares 17,045 Value ($000) $140 Avg Close $15.60 Range $7.79 - $26.25

Q3 2024

Shares 13,000 Value ($000) $220 Avg Close $17.98 Range $16.35 - $20.50

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	15,100	$548	$32.89	$18.33 - $44.60
Q3 2025	20,382	$452	$16.28	$8.91 - $22.45
Q2 2025	19,617	$190	$9.74	$6.11 - $12.56
Q4 2024	17,045	$140	$15.60	$7.79 - $26.25
Q3 2024	13,000	$220	$17.98	$16.35 - $20.50