ZOGENIX INC

CUSIP: 98978L105 Class: CMN

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 220,000 Value ($000) $2,515 Avg Close — Range —
Q2 2016
Shares 240,000 Value ($000) $1,932 Avg Close — Range —
Q4 2015
Shares 150,000 Value ($000) $2,211 Avg Close — Range —
Q3 2015
Shares 250,000 Value ($000) $3,375 Avg Close — Range —
Q2 2015
Shares 912,500 Value ($000) $1,533 Avg Close — Range —