ZYMEWORKS INC

CUSIP: 98985W102 Class: COM

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q4 2020
Shares 245,000 Value ($000) $11,579 Avg Close — Range —
Q3 2020
Shares 80,000 Value ($000) $3,726 Avg Close — Range —
Q2 2020
Shares 116,310 Value ($000) $4,195 Avg Close — Range —
Q1 2020
Shares 206,830 Value ($000) $7,336 Avg Close — Range —
Q4 2019
Shares 157,000 Value ($000) $7,137 Avg Close — Range —
Q3 2019
Shares 170,000 Value ($000) $4,216 Avg Close — Range —
Q3 2018
Shares 73,800 Value ($000) $1,159 Avg Close — Range —
Q2 2018
Shares 73,800 Value ($000) $1,091 Avg Close — Range —