ZYMEWORKS INC

Ticker: ZYME CUSIP: 98985Y108 Class: Common Stock

CHARLES SCHWAB INVESTMENT MANAGEMENT INC's Holding History (CIK: 0000884546)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 220,909 Value ($000) $5,817 Avg Close $21.81 Range $16.00 - $28.49

Q3 2025

Shares 193,360 Value ($000) $3,303 Avg Close $14.31 Range $11.51 - $17.60

Q2 2025

Shares 124,204 Value ($000) $1,559 Avg Close $11.91 Range $9.03 - $13.44

Q1 2025

Shares 133,639 Value ($000) $1,592 Avg Close $13.64 Range $10.96 - $17.07

Q4 2024

Shares 131,306 Value ($000) $1,922 Avg Close $13.98 Range $11.99 - $17.70

Q3 2024

Shares 132,798 Value ($000) $1,667 Avg Close $10.89 Range $8.32 - $13.27

Q2 2024

Shares 132,148 Value ($000) $1,125 Avg Close $8.90 Range $7.97 - $10.56

Q1 2024

Shares 125,491 Value ($000) $1,320 Avg Close $11.10 Range $9.64 - $13.14

Q4 2023

Shares 125,491 Value ($000) $1,304 Avg Close $7.97 Range $6.01 - $10.99

Q3 2023

Shares 121,866 Value ($000) $773 Avg Close $7.39 Range $6.11 - $8.80

Q2 2023

Shares 122,028 Value ($000) $1,054 Avg Close $8.95 Range $7.75 - $10.35

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	220,909	$5,817	$21.81	$16.00 - $28.49
Q3 2025	193,360	$3,303	$14.31	$11.51 - $17.60
Q2 2025	124,204	$1,559	$11.91	$9.03 - $13.44
Q1 2025	133,639	$1,592	$13.64	$10.96 - $17.07
Q4 2024	131,306	$1,922	$13.98	$11.99 - $17.70
Q3 2024	132,798	$1,667	$10.89	$8.32 - $13.27
Q2 2024	132,148	$1,125	$8.90	$7.97 - $10.56
Q1 2024	125,491	$1,320	$11.10	$9.64 - $13.14
Q4 2023	125,491	$1,304	$7.97	$6.01 - $10.99
Q3 2023	121,866	$773	$7.39	$6.11 - $8.80
Q2 2023	122,028	$1,054	$8.95	$7.75 - $10.35