ZYMEWORKS INC

Ticker: ZYME CUSIP: 98985Y108 Class: Common Stock

VIRGINIA RETIREMENT SYSTEMS ET AL's Holding History (CIK: 0001005354)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 27,935 Value ($000) $736 Avg Close $21.81 Range $16.00 - $28.49

Q3 2025

Shares 55,975 Value ($000) $956 Avg Close $14.31 Range $11.51 - $17.60

Q2 2025

Shares 54,075 Value ($000) $679 Avg Close $11.91 Range $9.03 - $13.44

Q1 2025

Shares 44,175 Value ($000) $526 Avg Close $13.64 Range $10.96 - $17.07

Q3 2023

Shares 116,100 Value ($000) $736 Avg Close $7.39 Range $6.11 - $8.80

Q2 2023

Shares 177,600 Value ($000) $1,534 Avg Close $8.95 Range $7.75 - $10.35

Q1 2023

Shares 81,600 Value ($000) $738 Avg Close $8.72 Range $7.31 - $10.80

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	27,935	$736	$21.81	$16.00 - $28.49
Q3 2025	55,975	$956	$14.31	$11.51 - $17.60
Q2 2025	54,075	$679	$11.91	$9.03 - $13.44
Q1 2025	44,175	$526	$13.64	$10.96 - $17.07
Q3 2023	116,100	$736	$7.39	$6.11 - $8.80
Q2 2023	177,600	$1,534	$8.95	$7.75 - $10.35
Q1 2023	81,600	$738	$8.72	$7.31 - $10.80